1VZO - chain A (model B) | Ribosomal protein S6 kinase A5
Structure information
PDB:1VZO
PubMed:15274926
Release date:2004-06-11
Resolution:1.8 Å
 
Kinase:RPS6KA5 (MSK1)
Family:RSK
Group:AGC
Species:HUMAN
 
Quality Score:7.2
Missing Residues:0
Missing Atoms:0
DFG conformation:in
αC-helix conformation:out
Salt bridge KIII.17 and EαC.24:No (19.3Å)
 
 
ASP rotation (xDFG.81) :342°
PHE rotation (xDFG.82) :267°
Activation loop position:-5.4Å
αC-helix position:25.9Å
 
G-rich loop angle:43.9°
G-rich loop distance:13.3Å
G-rich loop rotation:71.3°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
No waters were found in the defined clusters
Binding pocket sequence
UniprotKVLGTGAYGKVFLYAMKVLHTRTERQVLEHIRPFLVTLHYAHLILDYINGGELFTHLSQHLHKLGIIYRDIKLENILLLTDFGLS
Structure:KVLGTGAYGKVFLYAMKVLHTRTERQVLEHIRPFLVTLHYAHLILDYINGGELFTHLSQHLHKLGIIYRDIKLENILLLTDFGLS


Modified residues
No modified residues identified.