1TKI - chain A | Titin
Structure information
PDB:1TKI
PubMed:9804419
Release date:1999-06-08
Resolution:2 Å
 
Kinase:TTN
Family:MLCK
Group:CAMK
Species:HUMAN
 
Quality Score:8
Missing Residues:0
Missing Atoms:0
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:No (4.9Å)
 
 
ASP rotation (xDFG.81) :
PHE rotation (xDFG.82) :
Activation loop position:-5Å
αC-helix position:18.6Å
 
G-rich loop angle:63.2°
G-rich loop distance:19.9Å
G-rich loop rotation:33.7°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I4
H-bond protein
I10
H-bond protein
Binding pocket sequence
UniprotEDLGRGEFGIVHRYMAKFVLVKKEISILNIARRNILHLHESVMIFEFISGLDIFERINTFLHSHNIGHFDIRPENIIYIIEFGQA
Structure:EDLGRGEFGIVHRYMAKFVLVKKEISILNIARRNILHLHESVMIFEFISGLDIFERINTFLHSHNIGHFDIRPENIIYIIEFGQA


Modified residues
No modified residues identified.