1GZN - chain A | V-akt murine thymoma viral oncogene homolog 2
Structure information
| PDB: | 1GZN |
| PubMed: | 12086620 |
| Release date: | 2003-05-22 |
| Resolution: | 2.5 Å |
| Kinase: | AKT2 |
| Family: | Akt |
| Group: | AGC |
| Species: | HUMAN |
| Quality Score: | 5.6 |
| Missing Residues: | 3 |
| Missing Atoms: | 30 |
| DFG conformation: | out-like |
| αC-helix conformation: | in |
| Salt bridge KIII.17 and EαC.24: | No |
| ASP rotation (xDFG.81) : | 183° |
| PHE rotation (xDFG.82) : | 238° |
| Activation loop position: | 0.4Å |
| αC-helix position: | 18.7Å |
| G-rich loop angle: | 61.2° |
| G-rich loop distance: | 18.4Å |
| G-rich loop rotation: | 49.5° |
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
H-bond protein
I6
H-bond protein
I7
H-bond protein
I10
H-bond protein
Binding pocket sequence
| Uniprot | KLLGKGTFGKVILYAMKILHTVTESRVLQNTRPFLTALKYACFVMEYANGGELFFHLSRYLHSRDVVYRDIKLENLMLITDFGLC |
| Structure: | KLLGKGTFGKVILYAMKIL__VTESRVLQNTRPFLTALKYACFVMEYANGGELFFHLSRYLHSRDVVYRDIKLENLMLITDFGL_ |
Modified residues
No modified residues identified.