4HZR - chain A (model A) | Tyrosine kinase, non-receptor, 2
Structure information
PDB: | 4HZR |
PubMed: | 23342057 |
Release date: | 2013-02-06 |
Resolution: | 1.31 Å |
Kinase: | TNK2 (ACK) |
Family: | Ack |
Group: | TK |
Species: | HUMAN |
Quality Score: | 6.8 |
Missing Residues: | 3 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (3Å) |
ASP rotation (xDFG.81) : | 15° |
PHE rotation (xDFG.82) : | 14° |
Activation loop position: | -5Å |
αC-helix position: | 18.4Å |
G-rich loop angle: | - |
G-rich loop distance: | - |
G-rich loop rotation: | - |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
No H-bonds
I8
H-bond protein
I9
No H-bonds
Binding pocket sequence
Uniprot | EKLGDGSFGVVRRVAVKCLDFIREVNAMHSLDRNLIRLYGVKMVTELAPLGSLLDRLRKYLESKRFIHRDLAARNLLLIGDFGLM |
Structure: | EKLGDG___VVRRVAVKCLDFIREVNAMHSLDRNLIRLYGVKMVTELAPLGSLLDRLRKYLESKRFIHRDLAARNLLLIGDFGLM |
Modified residues
No modified residues identified.