3KN6 - chain B | Ribosomal protein S6 kinase A5 (2nd domain)
Structure information
PDB: | 3KN6 |
PubMed: | 20382163 |
Release date: | 2010-04-21 |
Resolution: | 2 Å |
Kinase: | RPS6KA5-b (MSK1-b) |
Family: | RSKb |
Group: | CAMK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (2.6Å) |
ASP rotation (xDFG.81) : | 338° |
PHE rotation (xDFG.82) : | 0° |
Activation loop position: | -3.9Å |
αC-helix position: | 18.3Å |
G-rich loop angle: | 54.6° |
G-rich loop distance: | 16.6Å |
G-rich loop rotation: | 53.1° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I8
H-bond protein
Binding pocket sequence
Uniprot | KPLGEGSFSICRKFAVKIINTQKEITALKLCEPNIVKLHEVFLVMELLNGGELFERIKKHMHDVGVVHRDLKPENLLFIIDFGFA |
Structure: | KPLGEGSFSICRKFAVKIINTQKEITALKLCEPNIVKLHEVFLVMELLNGGELFERIKKHMHDVGVVHRDLKPENLLFIIDFGFA |
Modified residues
No modified residues identified.