2V5Q - chain B (model B) | Polo like kinase 1
Structure information
| PDB: | 2V5Q |
| PubMed: | 18391401 |
| Release date: | 2008-04-01 |
| Resolution: | 2.3 Å |
| Kinase: | PLK1 |
| Family: | PLK |
| Group: | Other |
| Species: | HUMAN |
| Quality Score: | 9.8 |
| Missing Residues: | 0 |
| Missing Atoms: | 2 |
| DFG conformation: | in |
| αC-helix conformation: | in |
| Salt bridge KIII.17 and EαC.24: | Yes (3.8Å) |
| ASP rotation (xDFG.81) : | 338° |
| PHE rotation (xDFG.82) : | 13° |
| Activation loop position: | -3.1Å |
| αC-helix position: | 18.1Å |
| G-rich loop angle: | 58.4° |
| G-rich loop distance: | 16.6Å |
| G-rich loop rotation: | 64.6° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I2
H-bond protein
I4
H-bond protein
I5
H-bond protein
I7
H-bond protein
I8
H-bond protein
I11
No H-bonds
Binding pocket sequence
| Uniprot | RFLGKGGFAKCFEFAGKIVKMSMEISIHRSLAQHVVGFHGFFVVLELCRRRSLLELHKRYLHRNRVIHRDLKLGNLFLIGDFGLA |
| Structure: | RFLGKGGFAKCFEFAGKIVKMSMEISIHRSLAQHVVGFHGFFVVLELCRRRSLLELHKRYLHRNRVIHRDLKLGNLFLIGDFGLA |
Modified residues
No modified residues identified.