2V5Q - chain A (model A) | Polo like kinase 1
Structure information
PDB: | 2V5Q |
PubMed: | 18391401 |
Release date: | 2008-04-01 |
Resolution: | 2.3 Å |
Kinase: | PLK1 |
Family: | PLK |
Group: | Other |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (3.1Å) |
ASP rotation (xDFG.81) : | 332° |
PHE rotation (xDFG.82) : | 12° |
Activation loop position: | -3.3Å |
αC-helix position: | 17.8Å |
G-rich loop angle: | 55.9° |
G-rich loop distance: | 16Å |
G-rich loop rotation: | 59.9° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I2
H-bond protein
I4
H-bond protein
I5
H-bond protein
I7
H-bond protein
Binding pocket sequence
Uniprot | RFLGKGGFAKCFEFAGKIVKMSMEISIHRSLAQHVVGFHGFFVVLELCRRRSLLELHKRYLHRNRVIHRDLKLGNLFLIGDFGLA |
Structure: | RFLGKGGFAKCFEFAGKIVKMSMEISIHRSLAQHVVGFHGFFVVLELCRRRSLLELHKRYLHRNRVIHRDLKLGNLFLIGDFGLA |
Modified residues
No modified residues identified.