3L9P - chain A (model A) | Anaplastic lymphoma receptor tyrosine kinase
Structure information
PDB: | 3L9P |
PubMed: | 20632993 |
Release date: | 2010-07-28 |
Resolution: | 1.8 Å |
Kinase: | ALK |
Family: | ALK |
Group: | TK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | No |
ASP rotation (xDFG.81) : | 3° |
PHE rotation (xDFG.82) : | 19° |
Activation loop position: | -4.3Å |
αC-helix position: | 17.2Å |
G-rich loop angle: | 62.9° |
G-rich loop distance: | 18.8Å |
G-rich loop rotation: | 47.5° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I4
H-bond protein
I5
H-bond protein
Binding pocket sequence
Uniprot | RGLGHGAFGEVYEVAVKTLDFLMEALIISKFNQNIVRCIGVFILLELMAGGDLKSFLREYLEENHFIHRDIAARNCLLIGDFGMA |
Structure: | RGLGHGAFGEVYEVAVKTLDFLMEALIISKFNQNIVRCIGVFILLELMAGGDLKSFLREYLEENHFIHRDIAARNCLLIGDFGMA |
Modified residues
No modified residues identified.