2YJR - chain A (model A) | Anaplastic lymphoma receptor tyrosine kinase
Structure information
PDB: | 2YJR |
PubMed: | - |
Release date: | 2012-06-06 |
Resolution: | 1.9 Å |
Kinase: | ALK |
Family: | ALK |
Group: | TK |
Species: | HUMAN |
Quality Score: | 7.6 |
Missing Residues: | 1 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (3.1Å) |
ASP rotation (xDFG.81) : | 329° |
PHE rotation (xDFG.82) : | 9° |
Activation loop position: | -3.6Å |
αC-helix position: | 18.6Å |
G-rich loop angle: | 65.5° |
G-rich loop distance: | 19Å |
G-rich loop rotation: | 70.7° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I6
No H-bonds
Binding pocket sequence
Uniprot | RGLGHGAFGEVYEVAVKTLDFLMEALIISKFNQNIVRCIGVFILLELMAGGDLKSFLREYLEENHFIHRDIAARNCLLIGDFGMA |
Structure: | RGLGHGAFGEVYEVAVKTLDFLMEALIISKLNQNIVRCIGVFILLELMAGGDLKSFLREYLEENHFIHRDIAARNCLLIGDFGM_ |
Modified residues
No modified residues identified.