1FVR - chain A | TEK receptor tyrosine kinase
Structure information
PDB:1FVR
PubMed:11080633
Release date:2001-09-20
Resolution:2.2 Å
 
Kinase:TEK (TIE2)
Family:Tie
Group:TK
Species:HUMAN
 
Quality Score:8
Missing Residues:0
Missing Atoms:0
DFG conformation:out-like
αC-helix conformation:out
Salt bridge KIII.17 and EαC.24:No (7.4Å)
 
 
ASP rotation (xDFG.81) :119°
PHE rotation (xDFG.82) :285°
Activation loop position:-0.9Å
αC-helix position:20.9Å
 
G-rich loop angle:38.4°
G-rich loop distance:11.9Å
G-rich loop rotation:79.6°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I2
H-bond protein
I7
H-bond protein
Binding pocket sequence
UniprotDVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS
Structure:DVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS


Modified residues
No modified residues identified.