1FVR - chain B | TEK receptor tyrosine kinase
Structure information
PDB: | 1FVR |
PubMed: | 11080633 |
Release date: | 2001-09-20 |
Resolution: | 2.2 Å |
Kinase: | TEK (TIE2) |
Family: | Tie |
Group: | TK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | out-like |
αC-helix conformation: | out |
Salt bridge KIII.17 and EαC.24: | No (7.6Å) |
ASP rotation (xDFG.81) : | 121° |
PHE rotation (xDFG.82) : | 280° |
Activation loop position: | -1Å |
αC-helix position: | 20.9Å |
G-rich loop angle: | 38.5° |
G-rich loop distance: | 11.9Å |
G-rich loop rotation: | 80.9° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I2
H-bond protein
Binding pocket sequence
Uniprot | DVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS |
Structure: | DVIGEGNFGQVLKAAIKRMDFAGELEVLCKLGPNIINLLGAYLAIEYAPHGNLLDFLRKYLSQKQFIHRDLAARNILVIADFGLS |
Modified residues
No modified residues identified.