2QR7 - chain A (model A) | Ribosomal protein S6 kinase polypeptide 3 (2nd domain)
Structure information
PDB: | 2QR7 |
PubMed: | 18084304 |
Release date: | 2007-12-11 |
Resolution: | 2 Å |
Kinase: | Rps6ka3-b (RSK2-b) |
Family: | RSKb |
Group: | CAMK |
Species: | MOUSE |
Quality Score: | 7.6 |
Missing Residues: | 1 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (2.6Å) |
ASP rotation (xDFG.81) : | 342° |
PHE rotation (xDFG.82) : | 9° |
Activation loop position: | -3.6Å |
αC-helix position: | 18Å |
G-rich loop angle: | 57.6° |
G-rich loop distance: | 17.4Å |
G-rich loop rotation: | 37.7° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I4
H-bond protein
I5
H-bond protein
I10
H-bond protein
Binding pocket sequence
Uniprot | EDIGVGSYSVCKRFAVKIIDPTEEIEILLRYGPNIITLKDVYVVTELMKGGELLDKILRYLHAQGVVHRDLKPSNILYICDFGFA |
Structure: | EDIGVGSYSVCKRFAVKIIDPTEEIEILLRYGPNIITLKDVYVVTEL_KGGELLDKILRYLHAQGVVHRDLKPSNILYICDFGFA |
Modified residues
No modified residues identified.