5CEK - chain A | Tribbles pseudokinase 1
Structure information
PDB:5CEK
PubMed:26455797
Release date:2015-11-11
Resolution:2.8 Å
 
Kinase:TRIB1 (Trb1)
Family:Trbl
Group:CAMK
Species:HUMAN
 
Quality Score:6
Missing Residues:3
Missing Atoms:0
DFG conformation:out-like
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:No
 
 
ASP rotation (xDFG.81) :191°
PHE rotation (xDFG.82) :226°
Activation loop position:-2.1Å
αC-helix position:17.7Å
 
G-rich loop angle:-
G-rich loop distance:-
G-rich loop rotation:-
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
No waters were found in the defined clusters
Binding pocket sequence
UniprotLLLPLAEREHVSRLRCKVFYQDKIRPYIQLPSSNITGIVEVYVFFEKDF-GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE
Structure:LLLPLA___HVSRLRCKVFYQDKIRPYIQLPSSNITGIVEVYVFFEKDF_GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE


Modified residues
No modified residues identified.