5E8S - chain A (model B) | Transforming growth factor beta receptor I
Structure information
PDB: | 5E8S |
PubMed: | 27139629 |
Release date: | 2016-05-11 |
Resolution: | 1.45 Å |
Kinase: | TGFBR1 (TGFbR1) |
Family: | STKR |
Group: | TKL |
Species: | HUMAN |
Quality Score: | 9.8 |
Missing Residues: | 0 |
Missing Atoms: | 2 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (3.1Å) |
ASP rotation (xDFG.81) : | 359° |
PHE rotation (xDFG.82) : | 357° |
Activation loop position: | -3.3Å |
αC-helix position: | 17.5Å |
G-rich loop angle: | 54.5° |
G-rich loop distance: | 16.1Å |
G-rich loop rotation: | 61.7° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I2
H-bond protein
I5
H-bond protein
I8
H-bond protein
Binding pocket sequence
Uniprot | ESIGKGRFGEVWRVAVKIFSWFREAEIYQTVMENILGFIAAWLVSDYHEHGSLFDYLNRTQGKPAIAHRDLKSKNILVIADLGLA |
Structure: | ESIGKGRFGEVWRVAVKIFSWFREAEIYQTVMENILGFIAAWLVSDYHEHGSLFDYLNRTQGKPAIAHRDLKSKNILVIADLGLA |
Modified residues
No modified residues identified.