5E8V - chain A (model B) | Transforming growth factor beta receptor II
Structure information
| PDB: | 5E8V |
| PubMed: | 27139629 |
| Release date: | 2016-05-11 |
| Resolution: | 1.69 Å |
| Kinase: | TGFBR2 (TGFbR2) |
| Family: | STKR |
| Group: | TKL |
| Species: | HUMAN |
| Quality Score: | 8.8 |
| Missing Residues: | 0 |
| Missing Atoms: | 12 |
| DFG conformation: | in |
| αC-helix conformation: | in |
| Salt bridge KIII.17 and EαC.24: | Yes (2.7Å) |
| ASP rotation (xDFG.81) : | 4° |
| PHE rotation (xDFG.82) : | 20° |
| Activation loop position: | -3.2Å |
| αC-helix position: | 16.5Å |
| G-rich loop angle: | 48.8° |
| G-rich loop distance: | 14.9Å |
| G-rich loop rotation: | 58.9° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
No H-bonds
I5
H-bond protein
I8
H-bond protein
I9
H-bond protein
I11
H-bond protein
Binding pocket sequence
| Uniprot | TLVGKGRFAEVYKVAVKIFSWKTEKDIFSDINENILQFLTAWLITAFHAKGNLQEYLTRGRPKMPIVHRDLKSSNILVLCDFGLS |
| Structure: | TLVGKGRFAEVYKVAVKIFSWKTEKDIFSDINENILQFLTAWLITAFHAKGNLQEYLTRGRPKMPIVHRDLKSSNILVLCDFGLS |
Modified residues
No modified residues identified.