2WNT - chain A (model B) | Ribosomal protein S6 kinase A1 (2nd domain)
Structure information
PDB:2WNT
PubMed:-
Release date:2009-08-25
Resolution:2.4 Å
 
Kinase:RPS6KA1-b (RSK3-b)
Family:RSKb
Group:CAMK
Species:HUMAN
 
Quality Score:8
Missing Residues:0
Missing Atoms:21
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:Yes (3.3Å)
 
 
ASP rotation (xDFG.81) :358°
PHE rotation (xDFG.82) :15°
Activation loop position:-4.3Å
αC-helix position:17.9Å
 
G-rich loop angle:51.3°
G-rich loop distance:15.5Å
G-rich loop rotation:52.6°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I5
H-bond protein
Binding pocket sequence
UniprotETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA
Structure:ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA


Modified residues
No modified residues identified.