2WNT - chain B (model A) | Ribosomal protein S6 kinase A1 (2nd domain)
Structure information
PDB:2WNT
PubMed:-
Release date:2009-08-25
Resolution:2.4 Å
 
Kinase:RPS6KA1-b (RSK3-b)
Family:RSKb
Group:CAMK
Species:HUMAN
 
Quality Score:8.5
Missing Residues:0
Missing Atoms:15
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:Yes (2.7Å)
 
 
ASP rotation (xDFG.81) :357°
PHE rotation (xDFG.82) :17°
Activation loop position:-4.3Å
αC-helix position:18Å
 
G-rich loop angle:52.5°
G-rich loop distance:16.1Å
G-rich loop rotation:51.1°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I4
H-bond protein
I5
No H-bonds
Binding pocket sequence
UniprotETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA
Structure:ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA


Modified residues
No modified residues identified.