2WNT - chain A (model A) | Ribosomal protein S6 kinase A1 (2nd domain)
Structure information
PDB: | 2WNT |
PubMed: | - |
Release date: | 2009-08-25 |
Resolution: | 2.4 Å |
Kinase: | RPS6KA1-b (RSK3-b) |
Family: | RSKb |
Group: | CAMK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 21 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (3.3Å) |
ASP rotation (xDFG.81) : | 358° |
PHE rotation (xDFG.82) : | 15° |
Activation loop position: | -4.3Å |
αC-helix position: | 17.9Å |
G-rich loop angle: | 51.3° |
G-rich loop distance: | 15.5Å |
G-rich loop rotation: | 52.6° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I5
H-bond protein
Binding pocket sequence
Uniprot | ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA |
Structure: | ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA |
Modified residues
No modified residues identified.