5O2C - chain A | WNK lysine deficient protein kinase 3
Structure information
PDB: | 5O2C |
PubMed: | - |
Release date: | 2017-06-28 |
Resolution: | 2.4 Å |
Kinase: | WNK3 (Wnk3) |
Family: | WNK |
Group: | Other |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | out |
Salt bridge KIII.17 and EαC.24: | No |
ASP rotation (xDFG.81) : | 321° |
PHE rotation (xDFG.82) : | 339° |
Activation loop position: | -4.2Å |
αC-helix position: | 21.1Å |
G-rich loop angle: | 54.5° |
G-rich loop distance: | 16Å |
G-rich loop rotation: | 36.2° |
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
H-bond protein
Binding pocket sequence
Uniprot | IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA |
Structure: | IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA |
Modified residues
No modified residues identified.