5O21 - chain B | WNK lysine deficient protein kinase 3
Structure information
PDB: | 5O21 |
PubMed: | - |
Release date: | 2017-06-28 |
Resolution: | 2.06 Å |
Kinase: | WNK3 (Wnk3) |
Family: | WNK |
Group: | Other |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | out |
Salt bridge KIII.17 and EαC.24: | No |
ASP rotation (xDFG.81) : | 313° |
PHE rotation (xDFG.82) : | 10° |
Activation loop position: | -3.3Å |
αC-helix position: | 20.5Å |
G-rich loop angle: | 54.2° |
G-rich loop distance: | 16Å |
G-rich loop rotation: | 24.1° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
No H-bonds
I6
H-bond protein
Binding pocket sequence
Uniprot | IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA |
Structure: | IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA |
Modified residues
Residue 304 (not in pocket)
Phosphorylated serine