6BRU - chain A (model B) | Vaccinia related kinase 1
Structure information
PDB:6BRU
PubMed:-
Release date:2017-12-13
Resolution:1.8 Å
 
Kinase:VRK1
Family:VRK
Group:CK1
Species:HUMAN
 
Quality Score:9.6
Missing Residues:0
Missing Atoms:4
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:Yes (2.7Å)
 
 
ASP rotation (xDFG.81) :349°
PHE rotation (xDFG.82) :20°
Activation loop position:-3.2Å
αC-helix position:17.7Å
 
G-rich loop angle:48.5°
G-rich loop distance:14Å
G-rich loop rotation:64.9°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
H-bond protein
I5
H-bond protein
I11
H-bond protein
Binding pocket sequence
UniprotLPIGQGGFGCIYLCVVKVEPLFTELKFYQRAALGVPKYWGSFMIMDRFG-SDLQKIYEAYIHEHEYVHGDIKASNLLLLVDYGLA
Structure:LPIGQGGFGCIYLCVVKVEPLFTELKFYQRAALGVPKYWGSFMIMDRFG_SDLQKIYEAYIHEHEYVHGDIKASNLLLLVDYGLA


Modified residues
No modified residues identified.