3FZO - chain A | Protein tyrosine kinase 2 beta
Structure information
| PDB: | 3FZO |
| PubMed: | 19244237 |
| Release date: | 2009-03-31 |
| Resolution: | 2.2 Å |
| Kinase: | PTK2B (PYK2) |
| Family: | FAK |
| Group: | TK |
| Species: | HUMAN |
| Quality Score: | 8 |
| Missing Residues: | 0 |
| Missing Atoms: | 0 |
| DFG conformation: | in |
| αC-helix conformation: | in |
| Salt bridge KIII.17 and EαC.24: | Yes (4Å) |
| ASP rotation (xDFG.81) : | 69° |
| PHE rotation (xDFG.82) : | 0° |
| Activation loop position: | -4.9Å |
| αC-helix position: | 18.6Å |
| G-rich loop angle: | 70.1° |
| G-rich loop distance: | 19.9Å |
| G-rich loop rotation: | 68.4° |
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
H-bond protein
Binding pocket sequence
| Uniprot | RILGEGFFGEVYEVAVKTCKFMSEAVIMKNLDPHIVKLIGIWIIMELYPYGELGHYLERYLESINCVHRDIAVRNILVLGDFGLS |
| Structure: | RILGEGFFGEVYEVAVKTCKFMSEAVIMKNLDPHIVKLIGIWIIMELYPYGELGHYLERYLESINCVHRDIAVRNILVLGDFGLS |
Modified residues
No modified residues identified.