Browse kinase entries (page 6 of 191)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
AKT1AktAGC3qkmAn-(2-ethoxyethyl)-n-{(2s)-2-hydroxy-3-[(5r)-2-(quinazolin-4-yl)-2,7-diazaspiro[4.5]dec-7-yl]propyl}-2,6-dimethylbenzenesulfonamideHumanShow
AKT1AktAGC4ejnA-HumanShow
AKT1AktAGC4ekkAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT1AktAGC4ekkBphosphoaminophosphonic acid-adenylate esterHumanShow
AKT1AktAGC4eklA(2s)-2-(4-chlorophenyl)-1-{4-[(5r,7r)-7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-(propan-2-ylamino)propan-1-oneHumanShow
AKT1AktAGC4gv1AA4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT1AktAGC4gv1AB4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT1AktAGC5kcvA3-[3-[4-(1-azanylcyclobutyl)phenyl]-5-phenyl-imidazo[4,5-b]pyridin-2-yl]pyridin-2-amineHumanShow
AKT1AktAGC6buuAA-HumanShow
AKT1AktAGC6buuAB-HumanShow
AKT1AktAGC6buuAC-HumanShow
AKT1AktAGC6buuBA-HumanShow
AKT1AktAGC6buuBB-HumanShow
AKT1AktAGC6buuBC-HumanShow
AKT1AktAGC6c0iAA-HumanShow
AKT1AktAGC6c0iAB-HumanShow
AKT1AktAGC6c0iAC-HumanShow
AKT1AktAGC6c0iBA-HumanShow
AKT1AktAGC6c0iBB-HumanShow
AKT1AktAGC6c0iBC-HumanShow
AKT1AktAGC6ccyAA(5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-oneHumanShow
AKT1AktAGC6ccyAB(5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-oneHumanShow
AKT2AktAGC1gzkA-HumanShow
AKT2AktAGC1gznA-HumanShow
AKT2AktAGC1gzoA-HumanShow
AKT2AktAGC1mrvA-HumanShow
AKT2AktAGC1mryA-HumanShow
AKT2AktAGC1o6kAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT2AktAGC1o6lAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT2AktAGC2jdoAisoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amideHumanShow
AKT2AktAGC2jdrA(2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amineHumanShow
AKT2AktAGC2uw9A4-(4-chlorophenyl)-4-[4-(1h-pyrazol-4-yl)phenyl]piperidineHumanShow
AKT2AktAGC2x39A4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT2AktAGC2xh5A4-(4-tert-butylbenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminiumHumanShow
AKT2AktAGC3d0eA4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3d0eB4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e87AAn-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamideHumanShow
AKT2AktAGC3e87ABn-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamideHumanShow
AKT2AktAGC3e87BAn-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamideHumanShow
AKT2AktAGC3e87BBn-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamideHumanShow
AKT2AktAGC3e88A4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-6-{[(2r)-2-amino-3-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e88B4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-6-{[(2r)-2-amino-3-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e8dAA4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e8dAB4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e8dBA4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
AKT2AktAGC3e8dBB4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-olHumanShow
ALKALKTK2xb7A5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamineHumanShow
ALKALKTK2xbaA5-[(2r)-2-hydroxy-2-phenylacetyl]-3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-1,6-dihydropyrrolo[3,4-c]pyrazol-5-ium HumanShow
ALKALKTK2xp2A3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amineHumanShow
ALKALKTK2yfxA3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amineHumanShow
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