Browse kinase entries (page 6 of 205)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
AKT1AktAGC3cqwAB5-(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridineHumanShow
AKT1AktAGC3mv5AA(3r)-1-(5-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amineHumanShow
AKT1AktAGC3mv5AB(3r)-1-(5-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amineHumanShow
AKT1AktAGC3mvhAAn-{[(3s)-3-amino-1-(5-ethyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamideHumanShow
AKT1AktAGC3mvhABn-{[(3s)-3-amino-1-(5-ethyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamideHumanShow
AKT1AktAGC3o96A-HumanShow
AKT1AktAGC3ocbA(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amineHumanShow
AKT1AktAGC3ocbB(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amineHumanShow
AKT1AktAGC3ow4A(2r)-3-(1h-indol-3-yl)-1-{4-[(5s)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amineHumanShow
AKT1AktAGC3ow4B(2r)-3-(1h-indol-3-yl)-1-{4-[(5s)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amineHumanShow
AKT1AktAGC3qkkAn-(2-ethoxyethyl)-n-{(2s)-2-hydroxy-3-[(2r)-6-hydroxy-4-oxo-3,4-dihydro-1'h-spiro[chromene-2,3'-piperidin]-1'-yl]propyl}-2,6-dimethylbenzenesulfonamideHumanShow
AKT1AktAGC3qklAn-{(2s)-3-[(3s)-8',9'-dihydro-1h,3'h-spiro[piperidine-3,7'-pyrano[3,2-e]indazol]-1-yl]-2-hydroxypropyl}-n-(2-ethoxyethyl)-2,6-dimethylbenzenesulfonamideHumanShow
AKT1AktAGC3qkmAn-(2-ethoxyethyl)-n-{(2s)-2-hydroxy-3-[(5r)-2-(quinazolin-4-yl)-2,7-diazaspiro[4.5]dec-7-yl]propyl}-2,6-dimethylbenzenesulfonamideHumanShow
AKT1AktAGC4ejnA-HumanShow
AKT1AktAGC4ekkAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT1AktAGC4ekkBphosphoaminophosphonic acid-adenylate esterHumanShow
AKT1AktAGC4eklA(2s)-2-(4-chlorophenyl)-1-{4-[(5r,7r)-7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-(propan-2-ylamino)propan-1-oneHumanShow
AKT1AktAGC4gv1AA4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT1AktAGC4gv1AB4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT1AktAGC5kcvA3-[3-[4-(1-azanylcyclobutyl)phenyl]-5-phenyl-imidazo[4,5-b]pyridin-2-yl]pyridin-2-amineHumanShow
AKT1AktAGC6buuAA-HumanShow
AKT1AktAGC6buuAB-HumanShow
AKT1AktAGC6buuAC-HumanShow
AKT1AktAGC6buuBA-HumanShow
AKT1AktAGC6buuBB-HumanShow
AKT1AktAGC6buuBC-HumanShow
AKT1AktAGC6ccyAA(5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-oneHumanShow
AKT1AktAGC6ccyAB(5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-oneHumanShow
AKT1AktAGC6hhfAborussertibHumanShow
AKT1AktAGC6hhgA~{n}-[2-chloranyl-5-[[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]carbamoylamino]phenyl]propanamideHumanShow
AKT1AktAGC6hhhA~{n}-[4-[4-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperazin-1-yl]phenyl]propanamideHumanShow
AKT1AktAGC6hhiA~{n}-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]-3-(propanoylamino)benzamideHumanShow
AKT1AktAGC6hhjA~{n}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamideHumanShow
AKT1AktAGC6npzAA-HumanShow
AKT1AktAGC6npzAB-HumanShow
AKT1AktAGC6npzBA-HumanShow
AKT1AktAGC6npzBB-HumanShow
AKT2AktAGC1gzkA-HumanShow
AKT2AktAGC1gznA-HumanShow
AKT2AktAGC1gzoA-HumanShow
AKT2AktAGC1mrvA-HumanShow
AKT2AktAGC1mryA-HumanShow
AKT2AktAGC1o6kAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT2AktAGC1o6lAphosphoaminophosphonic acid-adenylate esterHumanShow
AKT2AktAGC2jdoAisoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amideHumanShow
AKT2AktAGC2jdrA(2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amineHumanShow
AKT2AktAGC2uw9A4-(4-chlorophenyl)-4-[4-(1h-pyrazol-4-yl)phenyl]piperidineHumanShow
AKT2AktAGC2x39A4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHumanShow
AKT2AktAGC2xh5A4-(4-tert-butylbenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminiumHumanShow
AKT2AktAGC3d0eA4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-olHumanShow
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