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Search results (54 entries covering 11 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
ROCK2DMPKAGC7jovFn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12759
ROCK2DMPKAGC4wotDmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6830
ROCK2DMPKAGC6p5mAB6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11915
ROCK2DMPKAGC4l6qA6-[4-(aminomethyl)-2-fluorophenoxy]-2,1-benzoxaborol-1(3h)-olHuman1811
ROCK2DMPKAGC6p5mDA-Human11925
ROCK2DMPKAGC7jovBn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12765
ROCK2DMPKAGC6p5pC2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11919
ROCK2DMPKAGC7jntBBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12766
ROCK2DMPKAGC6p5pA2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11914
ROCK2DMPKAGC5u7qB-Human7990
ROCK2DMPKAGC7jntABn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12754
ROCK2DMPKAGC7jntEBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12747
ROCK2DMPKAGC7p6nA~{n}-[(1~{r})-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-yl-piperidine-1-carboxamideHuman14314
ROCK2DMPKAGC8gdsA4-{4-[2-(2,3-dihydro-1h-indol-1-yl)-2-oxoethyl]phenyl}phthalazin-1(2h)-oneHuman14736
ROCK2DMPKAGC7jntGBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12767
ROCK2DMPKAGC7jovCn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12748
ROCK2DMPKAGC6p5mBA6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11921
ROCK2DMPKAGC6p5pB2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11923
ROCK2DMPKAGC7jntDAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12755
ROCK2DMPKAGC6p5mBB6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11924
ROCK2DMPKAGC6ed6Bn-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10688
ROCK2DMPKAGC4wotCmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6828
ROCK2DMPKAGC7jntBAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12756
ROCK2DMPKAGC7jntAAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12744
ROCK2DMPKAGC5u7rC(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7983
ROCK2DMPKAGC7jovHn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12751
ROCK2DMPKAGC7jntCBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12745
ROCK2DMPKAGC7jntEAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12746
ROCK2DMPKAGC7jntFAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12749
ROCK2DMPKAGC7jntDBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12750
ROCK2DMPKAGC6ed6An-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10689
ROCK2DMPKAGC6p5mAA6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11920
ROCK2DMPKAGC7jntCAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12752
ROCK2DMPKAGC7jntHBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12753
ROCK2DMPKAGC7jovAn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12757
ROCK2DMPKAGC6p5mCA-Human11917
ROCK2DMPKAGC6p5pD2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11918
ROCK2DMPKAGC4wotAmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6827
ROCK2DMPKAGC7jntFBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12758
ROCK2DMPKAGC5u7qA-Human7988
ROCK2DMPKAGC6p5mDB-Human11922
ROCK2DMPKAGC5u7qC-Human7987
ROCK2DMPKAGC7jntGAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12761
ROCK2DMPKAGC5u7qD-Human7986
ROCK2DMPKAGC6p5mCB-Human11916
ROCK2DMPKAGC5u7rD(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7985
ROCK2DMPKAGC7jovEn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12762
ROCK2DMPKAGC7jovGn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12763
ROCK2DMPKAGC7jntHAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12760
ROCK2DMPKAGC4l6qB6-[4-(aminomethyl)-2-fluorophenoxy]-2,1-benzoxaborol-1(3h)-olHuman1810
ROCK2DMPKAGC7jovDn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12764
ROCK2DMPKAGC4wotBmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6829
ROCK2DMPKAGC5u7rB(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7984
ROCK2DMPKAGC5u7rA(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7989
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