Search results (90 entries covering 32 PDB structures)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
ABL1AblTK3qrkA(3s)-6-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acidHumanShow
ABL1AblTK3cs9CAnilotinibHumanShow
ABL1AblTK3cs9BAnilotinibHumanShow
ABL1AblTK2hz0AA2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamideHumanShow
ABL1AblTK3ue4A4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHumanShow
ABL1AblTK2hziBB6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHumanShow
ABL1AblTK3qriAB4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK3qriAA4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK2e2bAn-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamideHumanShow
ABL1AblTK2g1tA-HumanShow
ABL1AblTK2gqgABn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK2g2fBphosphothiophosphoric acid-adenylate esterHumanShow
ABL1AblTK2hz4C-HumanShow
ABL1AblTK2g2fA-HumanShow
ABL1AblTK2g2hB6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK3qrjAA4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK3qriBB4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK4xeyAn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK3cs9DBnilotinibHumanShow
ABL1AblTK3cs9DAnilotinibHumanShow
ABL1AblTK2hz0AB2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamideHumanShow
ABL1AblTK4twpBaxitinibHumanShow
ABL1AblTK2e2bBn-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamideHumanShow
ABL1AblTK3qrjAB4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK2v7aBn-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamideHumanShow
ABL1AblTK4xeyBn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK3qrjBA4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK3ue4B4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHumanShow
ABL1AblTK2fo0A6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK2g1tC-HumanShow
ABL1AblTK4wa9AaxitinibHumanShow
ABL1AblTK2g1tD-HumanShow
ABL1AblTK2hyyD4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK2g2iBadenosine-5'-diphosphateHumanShow
ABL1AblTK3pyyBA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK2f4jAcyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amideHumanShow
ABL1AblTK2hziAB6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK2hyyB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK2hziAA6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK3cs9AAnilotinibHumanShow
ABL1AblTK2hz0BA2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamideHumanShow
ABL1AblTK4wa9BaxitinibHumanShow
ABL1AblTK2hyyA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK2gqgAAn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK2g2hA6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK2hiwB7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-iumHumanShow
ABL1AblTK3cs9ABnilotinibHumanShow
ABL1AblTK2hziBA6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK2g2iAadenosine-5'-diphosphateHumanShow
ABL1AblTK2hz0BB2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamideHumanShow
ABL1AblTK2g1tB-HumanShow
ABL1AblTK2hz4A-HumanShow
ABL1AblTK3qriBA4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK4twpAaxitinibHumanShow
ABL1AblTK3qrjBB4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamideHumanShow
ABL1AblTK4zogAcyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amideHumanShow
ABL1AblTK2hiwA7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-iumHumanShow
ABL1AblTK2hyyC4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK2v7aAn-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamideHumanShow
ABL1AblTK3pyyAA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK5mo4ABnilotinibHumanShow
ABL1AblTK4yc8B2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK4yc8A2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK5mo4AAnilotinibHumanShow
ABL1AblTK4zogBcyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amideHumanShow
ABL1AblTK5hu9AA4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamideHumanShow
ABL1AblTK2gqgBBn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK2gqgBAn-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideHumanShow
ABL1AblTK3pyyAB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK3pyyBB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK3cs9CBnilotinibHumanShow
ABL1AblTK3cs9BBnilotinibHumanShow
ABL1AblTK5hu9AB4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamideHumanShow
ABL1AblTK1oplB6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK1oplA6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHumanShow
ABL1AblTK6bl8BApurvalanol bHumanShow
ABL1AblTK6bl8BBpurvalanol bHumanShow
ABL1AblTK6bl8AApurvalanol bHumanShow
ABL1AblTK6bl8ABpurvalanol bHumanShow
ABL1AblTK6npuA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npeAB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npuB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npeBB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npeAA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npeBA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npvAA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npvBA4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npvBB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow
ABL1AblTK6npvAB4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamideHumanShow