2G1T - chain A | ABL proto-oncogene 1, non-receptor tyrosine kinase
Structure information
PDB:2G1T
PubMed:16640460
Release date:2006-05-23
Resolution:1.8 Å
 
Kinase:ABL1
Family:Abl
Group:TK
Species:HUMAN
 
Quality Score:8
Missing Residues:0
Missing Atoms:0
DFG conformation:in
αC-helix conformation:out
Salt bridge KIII.17 and EαC.24:No (14.4Å)
 
 
ASP rotation (xDFG.81) :312°
PHE rotation (xDFG.82) :313°
Activation loop position:-4.9Å
αC-helix position:21.5Å
 
G-rich loop angle:51.3°
G-rich loop distance:15.1Å
G-rich loop rotation:49.9°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I3
H-bond protein
I4
H-bond protein
I5
H-bond protein
I6
H-bond protein
Binding pocket sequence
UniprotHKLGGGQYGEVYEVAVKTLEFLKEAAVMKEIKPNLVQLLGVYIITEFMTYGNLLDYLREYLEKKNFIHRDLAARNCLVVADFGLS
Structure:HKLGGGQYGEVYEVAVKTLEFLKEAAVMKEIKPNLVQLLGVYIITEFMTYGNLLDYLREYLEKKNFIHRDLAARNCLVVADFGLS


Modified residues
No modified residues identified.