2G1T - chain A | ABL proto-oncogene 1, non-receptor tyrosine kinase
Structure information
PDB: | 2G1T |
PubMed: | 16640460 |
Release date: | 2006-05-23 |
Resolution: | 1.8 Å |
Kinase: | ABL1 |
Family: | Abl |
Group: | TK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | out |
Salt bridge KIII.17 and EαC.24: | No (14.4Å) |
ASP rotation (xDFG.81) : | 312° |
PHE rotation (xDFG.82) : | 313° |
Activation loop position: | -4.9Å |
αC-helix position: | 21.5Å |
G-rich loop angle: | 51.3° |
G-rich loop distance: | 15.1Å |
G-rich loop rotation: | 49.9° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I3
H-bond protein
I4
H-bond protein
I5
H-bond protein
I6
H-bond protein
Binding pocket sequence
Uniprot | HKLGGGQYGEVYEVAVKTLEFLKEAAVMKEIKPNLVQLLGVYIITEFMTYGNLLDYLREYLEKKNFIHRDLAARNCLVVADFGLS |
Structure: | HKLGGGQYGEVYEVAVKTLEFLKEAAVMKEIKPNLVQLLGVYIITEFMTYGNLLDYLREYLEKKNFIHRDLAARNCLVVADFGLS |
Modified residues
No modified residues identified.