6DC0 - chain A (model B) | Tribbles pseudokinase 1
Structure information
PDB:6DC0
PubMed:30254053
Release date:2018-10-10
Resolution:2.8 Å
 
Kinase:TRIB1 (Trb1)
Family:Trbl
Group:CAMK
Species:HUMAN
 
Quality Score:6.8
Missing Residues:0
Missing Atoms:0
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:No
 
 
ASP rotation (xDFG.81) :114°
PHE rotation (xDFG.82) :23°
Activation loop position:-1.3Å
αC-helix position:18.7Å
 
G-rich loop angle:71.4°
G-rich loop distance:21.2Å
G-rich loop rotation:19.3°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
No waters were found in the defined clusters
Binding pocket sequence
UniprotLLLPLAEREHVSRLRCKVFYQDKIRPYIQLPSSNITGIVEVYVFFEKDF-GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE
Structure:LLLPLAEREHVSRLRCKVFYQDKIRPYIQLPSSNITGIVEVYVFFEKDF_GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE


Modified residues
No modified residues identified.