1WAK - chain A | SRSF protein kinase 1
Structure information
| PDB: | 1WAK |
| PubMed: | 17223538 |
| Release date: | 2006-07-11 |
| Resolution: | 1.73 Å |
| Kinase: | SRPK1 |
| Family: | SRPK |
| Group: | CMGC |
| Species: | HUMAN |
| Quality Score: | 8 |
| Missing Residues: | 0 |
| Missing Atoms: | 0 |
| DFG conformation: | in |
| αC-helix conformation: | in |
| Salt bridge KIII.17 and EαC.24: | Yes (4.4Å) |
| ASP rotation (xDFG.81) : | 333° |
| PHE rotation (xDFG.82) : | 5° |
| Activation loop position: | -3.4Å |
| αC-helix position: | 18.3Å |
| G-rich loop angle: | 61.9° |
| G-rich loop distance: | 19.1Å |
| G-rich loop rotation: | 28.4° |
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I3
No H-bonds
I4
H-bond protein
I5
H-bond protein
I10
No H-bonds
Binding pocket sequence
| Uniprot | RKLGWGHFSTVWLVAMKVVTALDEIRLLKSVREMVVQLLDDCMVFEVLG-HHLLKWIIKLHTKCRIIHTDIKPENILLIADLGNA |
| Structure: | RKLGWGHFSTVWLVAMKVVTALDEIRLLKSVREMVVQLLDDCMVFEVLG_HHLLKWIIKLHTKCRIIHTDIKPENILLIADLGNA |
Modified residues
No modified residues identified.