1GZN - chain A | V-akt murine thymoma viral oncogene homolog 2
Structure information
PDB: | 1GZN |
PubMed: | 12086620 |
Release date: | 2003-05-22 |
Resolution: | 2.5 Å |
Kinase: | AKT2 |
Family: | Akt |
Group: | AGC |
Species: | HUMAN |
Quality Score: | 5.6 |
Missing Residues: | 3 |
Missing Atoms: | 30 |
DFG conformation: | out-like |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | No |
ASP rotation (xDFG.81) : | 183° |
PHE rotation (xDFG.82) : | 238° |
Activation loop position: | 0.4Å |
αC-helix position: | 18.7Å |
G-rich loop angle: | 61.2° |
G-rich loop distance: | 18.4Å |
G-rich loop rotation: | 49.5° |
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I1
H-bond protein
I3
H-bond protein
I6
H-bond protein
I7
H-bond protein
I10
H-bond protein
Binding pocket sequence
Uniprot | KLLGKGTFGKVILYAMKILHTVTESRVLQNTRPFLTALKYACFVMEYANGGELFFHLSRYLHSRDVVYRDIKLENLMLITDFGLC |
Structure: | KLLGKGTFGKVILYAMKIL__VTESRVLQNTRPFLTALKYACFVMEYANGGELFFHLSRYLHSRDVVYRDIKLENLMLITDFGL_ |
Modified residues
No modified residues identified.