5CEM - chain A (model A) | Tribbles pseudokinase 1
Structure information
PDB:5CEM
PubMed:26455797
Release date:2015-11-11
Resolution:2.1 Å
 
Kinase:TRIB1 (Trb1)
Family:Trbl
Group:CAMK
Species:HUMAN
 
Quality Score:6.4
Missing Residues:1
Missing Atoms:0
DFG conformation:out-like
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:No
 
 
ASP rotation (xDFG.81) :203°
PHE rotation (xDFG.82) :246°
Activation loop position:-2.4Å
αC-helix position:16.7Å
 
G-rich loop angle:79.1°
G-rich loop distance:22.6Å
G-rich loop rotation:32°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I5
H-bond protein
Binding pocket sequence
UniprotLLLPLAEREHVSRLRCKVFYQDKIRPYIQLPSSNITGIVEVYVFFEKDF-GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE
Structure:LLLPLAEREHVSRLRCKVFYQDKIRPYIQLP_SNITGIVEVYVFFEKDF_GDMHSYVRSHCHQSAIVLGDLKLRKFVFLRLESLE


Modified residues
No modified residues identified.