5CWZ - chain C | TRAF2 and NCK interacting kinase
Structure information
PDB:5CWZ
PubMed:27562646
Release date:2016-07-27
Resolution:2.9 Å
 
Kinase:TNIK
Family:STE20
Group:STE
Species:HUMAN
 
Quality Score:6.4
Missing Residues:4
Missing Atoms:0
DFG conformation:in
αC-helix conformation:in
Salt bridge KIII.17 and EαC.24:Yes (3.6Å)
 
 
ASP rotation (xDFG.81) :327°
PHE rotation (xDFG.82) :307°
Activation loop position:-4.9Å
αC-helix position:19.4Å
 
G-rich loop angle:50.8°
G-rich loop distance:15.1Å
G-rich loop rotation:49.5°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
No waters were found in the defined clusters
Binding pocket sequence
UniprotELVGNGTYGQVYKAAIKVMEIKQEINMLKKYSRNIATYYGAWLVMEFCGAGSVTDLIKNHLHQHKVIHRDIKGQNVLLLVDFGVS
Structure:ELVGNG__GQVYKAAIKVM_IKQEINMLKKYSRNIATYYGAWLVMEFCGAGSVTDLIKNHLHQHKVIHRDIKGQNVLLLVDFGV_


Modified residues
No modified residues identified.