5O23 - chain B (model B) | WNK lysine deficient protein kinase 3
Structure information
PDB:5O23
PubMed:-
Release date:2017-06-28
Resolution:2.25 Å
 
Kinase:WNK3 (Wnk3)
Family:WNK
Group:Other
Species:HUMAN
 
Quality Score:9.7
Missing Residues:0
Missing Atoms:3
DFG conformation:in
αC-helix conformation:out
Salt bridge KIII.17 and EαC.24:No
 
 
ASP rotation (xDFG.81) :49°
PHE rotation (xDFG.82) :18°
Activation loop position:-2.9Å
αC-helix position:22.5Å
 
G-rich loop angle:63.1°
G-rich loop distance:17.4Å
G-rich loop rotation:16.1°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I6
H-bond protein
Binding pocket sequence
UniprotIELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA
Structure:IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA


Modified residues
Residue 304 (not in pocket)
Phosphorylated serine