Searching for structures with analogs of Allitinib.

Search results (31 entries covering 15 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EGFREGFRTK4lrmCn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman7810.44
EGFREGFRTK4lrmDn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman7860.44
EGFREGFRTK4lqmAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman7850.59
TTBK1TTBKCK14btkA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman7710.41
EGFREGFRTK4ll0Bn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman7960.44
EGFREGFRTK4lrmEn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman8250.44
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.43
EGFREGFRTK4ll0An-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman8040.44
EGFREGFRTK4lrmBn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman8670.44
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.43
EGFREGFRTK2j5fAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman8620.59
EGFREGFRTK1xkkAn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamineHuman8440.57
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.43
ERBB4 (ErbB4)EGFRTK2r4bBAn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amineHuman28180.56
ERBB4 (ErbB4)EGFRTK3bbtDn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamineHuman28190.57
ERBB4 (ErbB4)EGFRTK2r4bAAn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amineHuman28220.56
ERBB4 (ErbB4)EGFRTK3bbtBn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamineHuman28250.57
EGFREGFRTK4lrmAn-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamideHuman9010.44
ERBB4 (ErbB4)EGFRTK2r4bABn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amineHuman28270.56
RETRetTK5amnA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman64120.41
JAK3JakATK4z16Dn-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamideHuman63940.40
JAK3JakATK4z16An-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamideHuman63950.40
ERBB4 (ErbB4)EGFRTK2r4bBBn-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amineHuman28230.56
JAK3JakATK4z16Bn-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamideHuman63960.40
JAK3JakATK4z16Cn-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamideHuman63970.40
CDK2CDKCMGC1di8A4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman45770.41
PRKACA (PKACa)PKAAGC6frxA~{n}-[3-[(5-chloranyl-2-phenylazanyl-pyrimidin-4-yl)amino]phenyl]prop-2-enamideHuman112610.43
TTBK2TTBKCK16u0kAA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120460.41
TTBK2TTBKCK16u0kBB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120470.41
TTBK2TTBKCK16u0kAB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120480.41
TTBK2TTBKCK16u0kBA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120490.41