Searching for structures with analogs of Sunitinib.

Search results (43 entries covering 20 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
ITKTecTK3miyBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman81.00
ITKTecTK3miyAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman461.00
NEK2NEKOther2javAB5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3230.56
NEK2NEKOther2javAA5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3320.56
KITPDGFRTK3g0eAAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4011.00
KITPDGFRTK3g0fBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4001.00
STK25 (YSK1)STE20STE4nzwB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4640.80
STK25 (YSK1)STE20STE2xikAA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4630.80
STK25 (YSK1)STE20STE2xikAB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4650.80
STK10 (LOK)STE20STE2j7tAA(3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxoindoline-5-sulfonamideHuman9460.40
STK10 (LOK)STE20STE2j7tAB(3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxoindoline-5-sulfonamideHuman9600.40
CAMK1G (CaMK1g)CAMK1CAMK2jamAA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12180.80
CAMK1G (CaMK1g)CAMK1CAMK2jamBA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12200.80
CAMK1G (CaMK1g)CAMK1CAMK2jamAB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12210.80
PHKG2 (PHKg2)PHKCAMK2y7jDAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18981.00
PHKG2 (PHKg2)PHKCAMK2y7jDBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18991.00
PHKG2 (PHKg2)PHKCAMK2y7jABn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18931.00
PHKG2 (PHKg2)PHKCAMK2y7jAAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18941.00
PHKG2 (PHKg2)PHKCAMK2y7jBBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18951.00
PHKG2 (PHKg2)PHKCAMK2y7jCAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18961.00
PHKG2 (PHKg2)PHKCAMK2y7jCBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman19001.00
CDK2CDKCMGC3ti1AAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman42011.00
CDK2CDKCMGC3ti1ABn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman42131.00
PAK6STE20STE4ks8ABn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman46801.00
PAK6STE20STE4ks8AAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman46831.00
KDRVEGFRTK4agdAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman53221.00
STK24 (MST3)STE20STE4qmzAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman55781.00
Tbk1 (TBK1)IKKOther4jlcA3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acidMouse56980.41
KITPDGFRTK3g0eABn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3981.00
CAMK1G (CaMK1g)CAMK1CAMK2jamBB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12190.80
PHKG2 (PHKg2)PHKCAMK2y7jBAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman18971.00
KITPDGFRTK3g0fAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3951.00
METMetTK2rfsAn-(3-chlorophenyl)-n-methyl-2-oxo-3-[(3,4,5-trimethyl-1h-pyrrol-2-yl)methyl]-2h-indole-5-sulfonamideHuman29740.41
CAMKK2 (CaMKK2)CAMKKOther5yvcA3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acidHuman107540.41
MAP4K1 (HPK1)STE20STE6nfzAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110781.00
MAP4K1 (HPK1)STE20STE6nfzBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110741.00
MAP4K1 (HPK1)STE20STE6ng0Bn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110731.00
MAP4K1 (HPK1)STE20STE6ng0An-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110711.00
MAP4K1 (HPK1)STE20STE6nfyBBn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110771.00
MAP4K1 (HPK1)STE20STE6nfyBAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110761.00
MAP4K1 (HPK1)STE20STE6nfyAAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110751.00
MAP4K1 (HPK1)STE20STE6nfyABn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman110721.00
PDGFRA (PDGFRa)PDGFRTK6jokAn-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman121051.00