Searching for structures with analogs of Tesevatinib.

Search results (26 entries covering 18 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EPHB4 (EphB4)EphTK2vwuAn-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amineHuman3700.46
EGFREGFRTK2ityAgefitinibHuman7900.49
EGFREGFRTK2itzAgefitinibHuman7890.49
TTBK1TTBKCK14btkA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman7710.40
EGFREGFRTK3ug2ABgefitinibHuman8190.49
EGFREGFRTK4i22AgefitinibHuman8230.49
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.40
EGFREGFRTK4wkqABgefitinibHuman8370.49
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.40
EGFREGFRTK4wkqAAgefitinibHuman8890.49
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.40
EGFREGFRTK3ug2AAgefitinibHuman8980.49
RETRetTK2ivuA4-bromo-2-fluoro-n-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1h)-ylidene]anilineHuman33640.59
KSR2RAFTKL5kkrB6,7-dimethoxy-~{n}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amineHuman70270.42
RETRetTK5amnA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman64120.40
EGFREGFRTK2itoAgefitinibHuman7830.49
CDK2CDKCMGC1di8A4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman45770.40
GAKNAKOther5y7zAgefitinibHuman103320.49
GAKNAKOther5y7zBgefitinibHuman103310.49
GAKNAKOther5y80ABgefitinibHuman103300.49
GAKNAKOther5y80AAgefitinibHuman103290.49
TTBK2TTBKCK16u0kAA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120460.40
TTBK2TTBKCK16u0kBB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120470.40
TTBK2TTBKCK16u0kAB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120480.40
TTBK2TTBKCK16u0kBA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120490.40
MAPK14 (p38a)MAPKCMGC1di9A4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazolineHuman52510.42