Searching for structures with analogs of Vandetanib.

Search results (26 entries covering 18 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EPHB4 (EphB4)EphTK2vwuAn-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amineHuman3700.40
EGFREGFRTK2ityAgefitinibHuman7900.47
EGFREGFRTK2itzAgefitinibHuman7890.47
TTBK1TTBKCK14btkA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman7710.41
EGFREGFRTK3ug2ABgefitinibHuman8190.47
EGFREGFRTK4i22AgefitinibHuman8230.47
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.40
EGFREGFRTK4wkqABgefitinibHuman8370.47
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.40
EGFREGFRTK4wkqAAgefitinibHuman8890.47
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.40
EGFREGFRTK3ug2AAgefitinibHuman8980.47
RETRetTK2ivuA4-bromo-2-fluoro-n-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1h)-ylidene]anilineHuman33641.00
KSR2RAFTKL5kkrB6,7-dimethoxy-~{n}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amineHuman70270.42
RETRetTK5amnA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman64120.41
EGFREGFRTK2itoAgefitinibHuman7830.47
CDK2CDKCMGC1di8A4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman45770.41
GAKNAKOther5y7zAgefitinibHuman103320.47
GAKNAKOther5y7zBgefitinibHuman103310.47
GAKNAKOther5y80ABgefitinibHuman103300.47
GAKNAKOther5y80AAgefitinibHuman103290.47
TTBK2TTBKCK16u0kAA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120460.41
TTBK2TTBKCK16u0kBB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120470.41
TTBK2TTBKCK16u0kAB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120480.41
TTBK2TTBKCK16u0kBA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120490.41
MAPK14 (p38a)MAPKCMGC1di9A4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazolineHuman52510.42