Searching for structures with analogs of Canertinib.

Search results (35 entries covering 24 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EPHB4 (EphB4)EphTK2vwuAn-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amineHuman3700.46
EGFREGFRTK2ityAgefitinibHuman7900.73
EGFREGFRTK4lqmAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman7850.42
EGFREGFRTK2itzAgefitinibHuman7890.73
EGFREGFRTK3ug2ABgefitinibHuman8190.73
EGFREGFRTK4i22AgefitinibHuman8230.73
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.60
EGFREGFRTK4g5pAn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman8090.57
EGFREGFRTK4wkqABgefitinibHuman8370.73
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.60
EGFREGFRTK2j5fAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman8620.42
EGFREGFRTK4g5jABn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman8520.57
EGFREGFRTK4wkqAAgefitinibHuman8890.73
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.60
EGFREGFRTK3ug2AAgefitinibHuman8980.73
MAPK14 (p38a)MAPKCMGC4a9yAn-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamideHuman50730.42
MAPK14 (p38a)MAPKCMGC2bakAn-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamideHuman51140.42
EGFREGFRTK4g5jAAn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman7940.57
METMetTK3lq8ABn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman29640.42
METMetTK3lq8AAn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman29980.42
EGFREGFRTK2itoAgefitinibHuman7830.73
EPHA2 (EphA2)EphTK5ia4ABn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman71680.42
EPHA2 (EphA2)EphTK5ia4AAn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman71890.42
PKMYT1 (MYT1)WEEOther5vcwA(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamideHuman83350.43
PKMYT1 (MYT1)WEEOther5vcwB(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamideHuman83460.43
GAKNAKOther5y7zAgefitinibHuman103320.73
GAKNAKOther5y7zBgefitinibHuman103310.73
GAKNAKOther5y80ABgefitinibHuman103300.73
GAKNAKOther5y80AAgefitinibHuman103290.73
EGFREGFRTK5y25A(2r)-n-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamideHuman103730.72
STK10 (LOK)STE20STE6i2yAn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman107870.42
STK10 (LOK)STE20STE6i2yBn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman107880.42
METMetTK6sdcABn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman115340.42
METMetTK6sdcAAn-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman115320.42
METMetTK6sd9An-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHuman115310.42