Searching for structures with analogs of Duvelisib.

Search results (17 entries covering 9 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
TNNI3K (HH498)MLKTKL4yfiAAn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60590.41
TNNI3K (HH498)MLKTKL4yfiBBn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60600.41
TNNI3K (HH498)MLKTKL4yfiBAn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60610.41
TNNI3K (HH498)MLKTKL4yfiDBn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60640.41
TNNI3K (HH498)MLKTKL4yfiCAn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60700.41
TNNI3K (HH498)MLKTKL4yfiDAn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60720.41
TNNI3K (HH498)MLKTKL4yfiABn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60710.41
TNNI3K (HH498)MLKTKL4yfiCBn-methyl-3-(9h-purin-6-ylamino)benzenesulfonamideHuman60730.41
PIK3CG (p110g)PIKAtypical4wwoAn-{(1s)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}-9h-purin-6-amineHuman91900.49
PIK3CG (p110g)PIKAtypical2chwA2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-oneHuman91820.44
PIK3CG (p110g)PIKAtypical4wwpAn-{(1s)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9h-purin-6-amineHuman92000.50
PIK3CG (p110g)PIKAtypical4wwnAn-{(1s)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl}-9h-purin-6-amineHuman92260.43
Pik3cd (p110d)PIKAtypical2wxfAB2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-oneMouse93520.44
Pik3cd (p110d)PIKAtypical2wxfAA2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-oneMouse93550.44
Pik3cd (p110d)PIKAtypical4xe0A5-fluoro-3-phenyl-2-[(1s)-1-(7h-purin-6-ylamino)propyl]quinazolin-4(3h)-oneMouse93680.42
Pik3cd (p110d)PIKAtypical5i4uA2,4-diamino-6-{[(1s)-1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]amino}pyrimidine-5-carbonitrileMouse93910.42
Pik3cd (p110d)PIKAtypical5i6uA2-[(1s)-1-({6-amino-5-[(1h-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3h)-oneMouse93700.46