Browse kinase entries (page 206 of 214)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
TYK2JakATK4gfoAA2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamideHumanShow
TYK2JakATK4gfoAB2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamideHumanShow
TYK2JakATK4gihAA2,6-dichloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamideHumanShow
TYK2JakATK4gihAB2,6-dichloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamideHumanShow
TYK2JakATK4giiA2,6-dichloro-4-cyano-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamideHumanShow
TYK2JakATK4gj2A2,6-dichloro-n-[2-({[(1r,2r)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamideHumanShow
TYK2JakATK4gj3A2,6-dichloro-4-cyano-n-[2-({[(1r,2r)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamideHumanShow
TYK2JakATK4gvjAadenosine-5'-diphosphateHumanShow
TYK2JakATK4py1A6-[(2,5-dimethoxyphenyl)sulfanyl]-3-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazineHumanShow
TYK2JakATK5f1zAA3-azanyl-5-[(2~{s})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{h}-pyrazolo[4,3-c]pyridin-4-oneHumanShow
TYK2JakATK5f1zAB3-azanyl-5-[(2~{s})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{h}-pyrazolo[4,3-c]pyridin-4-oneHumanShow
TYK2JakATK5f20A3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{h}-pyrazolo[4,3-c]pyridin-4-oneHumanShow
TYK2JakATK5walAAn-[2-(2,6-dichlorophenyl)-1h-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamideHumanShow
TYK2JakATK5walABn-[2-(2,6-dichlorophenyl)-1h-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamideHumanShow
TYK2JakATK6aamA4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamideHumanShow
TYK2JakATK6dbkA4-({4-[(1s,4s)-5-(cyanoacetyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyrimidin-2-yl}amino)-n-ethylbenzamideHumanShow
TYK2JakATK6dbmAA[(1s)-2,2-difluorocyclopropyl][(1r,5s)-3-{2-[(1-methyl-1h-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanoneHumanShow
TYK2JakATK6dbmAB[(1s)-2,2-difluorocyclopropyl][(1r,5s)-3-{2-[(1-methyl-1h-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanoneHumanShow
TYK2JakATK6ovaAA6-({4-[(3s)-3-cyano-3-cyclopropyl-2-oxopyrrolidin-1-yl]pyridin-2-yl}amino)-n,n-dimethylpyridine-3-carboxamideHumanShow
TYK2JakATK6ovaAB6-({4-[(3s)-3-cyano-3-cyclopropyl-2-oxopyrrolidin-1-yl]pyridin-2-yl}amino)-n,n-dimethylpyridine-3-carboxamideHumanShow
TYK2-bJakBTK3zonA5-phenyl-2-ureidothiophene-3-carboxamideHumanShow
TYK2-bJakBTK4oliA2-chloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamideHumanShow
TYK2-bJakBTK4wovAA2-methoxy-n-({6-[1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]pyridin-2-yl}methyl)acetamideHumanShow
TYK2-bJakBTK4wovAB2-methoxy-n-({6-[1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]pyridin-2-yl}methyl)acetamideHumanShow
TYK2-bJakBTK4wovBA2-methoxy-n-({6-[1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]pyridin-2-yl}methyl)acetamideHumanShow
TYK2-bJakBTK4wovBB2-methoxy-n-({6-[1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]pyridin-2-yl}methyl)acetamideHumanShow
TYK2-bJakBTK5c01Aunknown ligandHumanShow
TYK2-bJakBTK5c01Bunknown ligandHumanShow
TYK2-bJakBTK5c03AAphosphothiophosphoric acid-adenylate esterHumanShow
TYK2-bJakBTK5c03ABphosphothiophosphoric acid-adenylate esterHumanShow
TYK2-bJakBTK5c03BAphosphothiophosphoric acid-adenylate esterHumanShow
TYK2-bJakBTK5c03BBphosphothiophosphoric acid-adenylate esterHumanShow
TYK2-bJakBTK5tkdAA6-[(3,5-dimethylphenyl)amino]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK5tkdAB6-[(3,5-dimethylphenyl)amino]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK5tkdBA6-[(3,5-dimethylphenyl)amino]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK5tkdBB6-[(3,5-dimethylphenyl)amino]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK6nslAA6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-n-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK6nslAB6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-n-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK6nslBA6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-n-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK6nslBB6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-n-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamideHumanShow
TYK2-bJakBTK6nzeAA4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzeAB4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzeBA4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzeBB4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzfAA6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzfAB6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzfBA6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzfBB6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzhAA6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
TYK2-bJakBTK6nzhAB6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHumanShow
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