4GT4 - chain B (model B) | Receptor tyrosine kinase-like orphan receptor 2
Structure information
PDB:4GT4
PubMed:22992069
Release date:2012-09-26
Resolution:2.41 Å
 
Kinase:ROR2
Family:Ror
Group:TK
Species:HUMAN
 
Quality Score:7.6
Missing Residues:0
Missing Atoms:26
DFG conformation:out-like
αC-helix conformation:out
Salt bridge KIII.17 and EαC.24:Yes (3Å)
 
 
ASP rotation (xDFG.81) :160°
PHE rotation (xDFG.82) :225°
Activation loop position:-0.6Å
αC-helix position:21.6Å
 
G-rich loop angle:65°
G-rich loop distance:18.6Å
G-rich loop rotation:81.6°
Other models from this PDB:
2D & 3D views

The orthosteric binding pocket
Binding pocket waters
The following waters were found in the defined clusters:
I7
H-bond protein
I9
H-bond protein
Binding pocket sequence
UniprotEELGEDRFGKVYKVAIKTLEFRHEAMLRARLQPNVVCLLGVSMIFSYCSHGDLHEFLVMYLSSHHVVHKDLATRNVLVISDLGLF
Structure:EELGEDRFGKVYKVAIKTLEFRHEAMLRARLQPNVVCLLGVSMIFSYCSHGDLHEFLVMYLSSHHVVHKDLATRNVLVISDLGLF


Modified residues
No modified residues identified.