4GT4 - chain B (model A) | Receptor tyrosine kinase-like orphan receptor 2
Structure information
PDB: | 4GT4 |
PubMed: | 22992069 |
Release date: | 2012-09-26 |
Resolution: | 2.41 Å |
Kinase: | ROR2 |
Family: | Ror |
Group: | TK |
Species: | HUMAN |
Quality Score: | 7.6 |
Missing Residues: | 0 |
Missing Atoms: | 26 |
DFG conformation: | out-like |
αC-helix conformation: | out |
Salt bridge KIII.17 and EαC.24: | Yes (3Å) |
ASP rotation (xDFG.81) : | 160° |
PHE rotation (xDFG.82) : | 225° |
Activation loop position: | -0.6Å |
αC-helix position: | 21.6Å |
G-rich loop angle: | 65° |
G-rich loop distance: | 18.6Å |
G-rich loop rotation: | 81.6° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I7
H-bond protein
I9
H-bond protein
Binding pocket sequence
Uniprot | EELGEDRFGKVYKVAIKTLEFRHEAMLRARLQPNVVCLLGVSMIFSYCSHGDLHEFLVMYLSSHHVVHKDLATRNVLVISDLGLF |
Structure: | EELGEDRFGKVYKVAIKTLEFRHEAMLRARLQPNVVCLLGVSMIFSYCSHGDLHEFLVMYLSSHHVVHKDLATRNVLVISDLGLF |
Modified residues
No modified residues identified.