4NIF - chain A (model B) | Ribosomal protein S6 kinase A1 (2nd domain)
Structure information
PDB: | 4NIF |
PubMed: | 25730857 |
Release date: | 2014-11-12 |
Resolution: | 2.15 Å |
Kinase: | RPS6KA1-b (RSK3-b) |
Family: | RSKb |
Group: | CAMK |
Species: | HUMAN |
Quality Score: | 8 |
Missing Residues: | 0 |
Missing Atoms: | 0 |
DFG conformation: | in |
αC-helix conformation: | in |
Salt bridge KIII.17 and EαC.24: | Yes (2.6Å) |
ASP rotation (xDFG.81) : | 342° |
PHE rotation (xDFG.82) : | 9° |
Activation loop position: | -3.6Å |
αC-helix position: | 18Å |
G-rich loop angle: | 52.5° |
G-rich loop distance: | 15.6Å |
G-rich loop rotation: | 62.2° |
Other models from this PDB:
2D & 3D views
Binding pocket waters
The following waters were found in the defined clusters:
I3
H-bond protein
I4
H-bond protein
I5
H-bond protein
Binding pocket sequence
Uniprot | ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA |
Structure: | ETIGVGSYSECKRYAVKVIDPSEEIEILLRYGPNIITLKDVYLVTELMRGGELLDKILRYLHSQGVVHRDLKPSNILYICDFGFA |
Modified residues
No modified residues identified.