| TTK | TTK | Other | 5nad | A | | bay 1217389 | Human | 7975 | |
| TTK | TTK | Other | 6tnd | A | B | bay 1217389 | Human | 12272 | |
| TTK | TTK | Other | 3h9f | A | B | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4712 | |
| TTK | TTK | Other | 3hmn | A | | adenosine-5'-triphosphate | Human | 4719 | |
| TTK | TTK | Other | 6tn9 | A | B | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12269 | |
| TTK | TTK | Other | 5n7v | A | | ~{n}6-cyclohexyl-~{n}2-(2-methyl-4-morpholin-4-yl-phenyl)-7~{h}-purine-2,6-diamine | Human | 7978 | |
| TTK | TTK | Other | 4bi1 | A | | thieno[3,2-c][2,6]naphthyridine | Human | 4699 | |
| TTK | TTK | Other | 5o91 | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8269 | |
| TTK | TTK | Other | 3h9f | A | A | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4701 | |
| TTK | TTK | Other | 6tnc | A | | n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | Human | 12270 | |
| TTK | TTK | Other | 5ljj | A | | n~6~-cyclohexyl-n~2~-(4-morpholin-4-ylphenyl)-9h-purine-2,6-diamine | Human | 7092 | |
| TTK | TTK | Other | 4c4i | A | | tert-butyl 6-{[2-chloro-4-(dimethylcarbamoyl)phenyl]amino}-2-(1,3-oxazol-5-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4698 | |
| TTK | TTK | Other | 3wyy | A | | (2e)-3-[4-({4-amino-5-cyano-6-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylamino]pyridin-2-yl}amino)-2-(cyanomethoxy)phenyl]-n-(2-methoxyethyl)prop-2-enamide | Human | 4711 | |
| TTK | TTK | Other | 3wyx | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 4721 | |
| TTK | TTK | Other | 5ei6 | A | | ~{n}-(2,4-dimethoxyphenyl)-5-(1-methylpyrazol-4-yl)isoquinolin-3-amine | Human | 6558 | |
| TTK | TTK | Other | 4c4e | A | A | n-(3,4-dimethoxyphenyl)-2-(1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridin-6-amine | Human | 4708 | |
| TTK | TTK | Other | 3vqu | A | | 4-[(4-amino-5-cyano-6-ethoxypyridin-2-yl)amino]benzamide | Human | 4718 | |
| TTK | TTK | Other | 4cv9 | A | | 4-(4-methylpiperazin-1-yl)-n-(2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin-3-yl)benzamide | Human | 4705 | |
| TTK | TTK | Other | 5ntt | A | A | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8268 | |
| TTK | TTK | Other | 5ap1 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6103 | |
| TTK | TTK | Other | 6n6o | A | | 4-({5-chloro-4-[(cis-4-hydroxy-4-methylcyclohexyl)oxy]-7h-pyrrolo[2,3-d]pyrimidin-2-yl}amino)-n,n-dimethyl-3-{[(2r)-1,1,1-trifluoropropan-2-yl]oxy}benzamide | Human | 11240 | |
| TTK | TTK | Other | 6tnb | A | | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | 12267 | |
| TTK | TTK | Other | 5ehy | A | | 4-(furan-3-yl)-3-phenyl-2~{h}-pyrazolo[4,3-c]pyridine | Human | 6556 | |
| TTK | TTK | Other | 7chn | A | | 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13552 | |
| TTK | TTK | Other | 3w1f | A | | 5-[5-ethoxy-6-(1-methyl-1h-pyrazol-4-yl)-1h-indazol-3-yl]-2-methylbenzenesulfonamide | Human | 4722 | |
| TTK | TTK | Other | 3wzk | A | | n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | Human | 4703 | |
| TTK | TTK | Other | 3hmo | A | | staurosporine | Human | 4707 | |
| TTK | TTK | Other | 4c4j | A | | tert-butyl 6-{[2-chloro-4-(1-methyl-1h-imidazol-5-yl)phenyl]amino}-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4723 | |
| TTK | TTK | Other | 7cja | A | | 4-(cyclopentylmethylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13551 | |
| TTK | TTK | Other | 3wzj | A | | 4-{6-(cyclohexylamino)-8-[(tetrahydro-2h-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-n-cyclopropylbenzamide | Human | 4704 | |
| TTK | TTK | Other | 5ei8 | A | | ~{n}-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6557 | |
| TTK | TTK | Other | 4c4g | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4697 | |
| TTK | TTK | Other | 6b4w | A | | 4-{[4-(cyclopentyloxy)-5-(2-methyl-1,3-benzoxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl]amino}-3-methoxy-n-methylbenzamide | Human | 8616 | |
| TTK | TTK | Other | 4c4f | A | | n-(2-methoxyphenyl)-2-(1,3-oxazol-5-yl)-1h-pyrrolo[3,2-c]pyridin-6-amine | Human | 4715 | |
| TTK | TTK | Other | 4cva | A | | n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)-4-(piperidin-1-yl)benzamide | Human | 4713 | |
| TTK | TTK | Other | 5ei2 | A | | ~{n}-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6559 | |
| TTK | TTK | Other | 5ap4 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6097 | |
| TTK | TTK | Other | 2zmc | A | | - | Human | 4696 | |
| TTK | TTK | Other | 7cil | A | B | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13555 | |
| TTK | TTK | Other | 5ap3 | A | | 9-cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8h-purin-8-one | Human | 6099 | |
| TTK | TTK | Other | 7cil | A | A | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13549 | |
| TTK | TTK | Other | 7clh | A | | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(methylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13553 | |
| TTK | TTK | Other | 2zmd | A | | 2,6-dihydroanthra/1,9-cd/pyrazol-6-one | Human | 4731 | |
| TTK | TTK | Other | 4o6l | A | | n-[(1r)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1h-indazole-5-carboxamide | Human | 4730 | |
| TTK | TTK | Other | 4bi0 | A | | 5h-pyrimido[5,4-b]indole | Human | 4702 | |
| TTK | TTK | Other | 5ntt | A | B | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8267 | |
| TTK | TTK | Other | 3gfw | A | | 1-(4-(4-(2-(isopropylsulfonyl)phenylamino)-1h-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol | Human | 4714 | |
| TTK | TTK | Other | 5ehl | A | | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 7256 | |
| TTK | TTK | Other | 5mrb | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8270 | |
| TTK | TTK | Other | 5ap0 | A | | 9-cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8h-purin-8-one | Human | 6101 | |
| TTK | TTK | Other | 4jt3 | A | | 2-phenyl-n-[3-(3-sulfamoylphenyl)-2h-indazol-5-yl]acetamide | Human | 4727 | |
| TTK | TTK | Other | 5n9s | A | | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | 7979 | |
| TTK | TTK | Other | 6gvj | A | | - | Human | 10847 | |
| TTK | TTK | Other | 5n93 | A | | 4-[[4-azanyl-6-(~{tert}-butylamino)-5-cyano-pyridin-2-yl]amino]benzamide | Human | 7976 | |
| TTK | TTK | Other | 5n84 | A | | ~{n}-cyclopropyl-4-[8-(2-methylpropylamino)imidazo[1,2-a]pyrazin-3-yl]benzamide | Human | 7973 | |
| TTK | TTK | Other | 5na0 | A | | ~{n}-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]pyrazol-4-yl]-2-[[2-methoxy-4-[4-(2-methoxyethanoyl)piperazin-1-yl]phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7974 | |
| TTK | TTK | Other | 5ap6 | A | A | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6098 | |
| TTK | TTK | Other | 4js8 | A | | 4-(cyclohexylmethoxy)-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-2h-indazole | Human | 4724 | |
| TTK | TTK | Other | 4bhz | A | | thieno[2,3-c][2,6]naphthyridine | Human | 4709 | |
| TTK | TTK | Other | 7cht | A | | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13554 | |
| TTK | TTK | Other | 6h3k | A | | ~{n}8-(2,2-dimethylpropyl)-~{n}2-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methyl-pyrido[3,4-d]pyrimidine-2,8-diamine | Human | 10571 | |
| TTK | TTK | Other | 4bi2 | A | | thieno[2,3-c][2,7]naphthyridine | Human | 4700 | |
| TTK | TTK | Other | 2x9e | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4729 | |
| TTK | TTK | Other | 7chm | A | | 4-(cyclohexylamino)-2-[(2-methoxy-4-morpholin-4-ylcarbonyl-phenyl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13550 | |
| TTK | TTK | Other | 5n87 | A | | ~{n}-(2,6-diethylphenyl)-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7977 | |
| TTK | TTK | Other | 6tnd | A | A | bay 1217389 | Human | 12268 | |
| TTK | TTK | Other | 5ap2 | A | | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6105 | |
| TTK | TTK | Other | 4zeg | A | | n-cyclopropyl-2-methyl-4-(7-{[2-(morpholin-4-yl)ethyl]amino}-5-phenoxypyrazolo[1,5-a]pyrimidin-3-yl)benzamide | Human | 6574 | |
| TTK | TTK | Other | 7lqd | A | | ~{n}-(2,6-diethylphenyl)-2-[[4-(4-methylpiperazin-1-yl)-2-(propanoylamino)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 14108 | |
| TTK | TTK | Other | 6tn9 | A | A | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12271 | |
| TTK | TTK | Other | 5ap6 | A | B | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6102 | |
| TTK | TTK | Other | 3cek | A | | - | Human | 4716 | |
| TTK | TTK | Other | 4cv8 | A | | 3-amino-5-(1-methyl-1h-pyrazol-4-yl)pyridin-2(1h)-one | Human | 4706 | |
| TTK | TTK | Other | 4c4h | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4725 | |
| TTK | TTK | Other | 3dbq | A | | - | Human | 4710 | |
| TTK | TTK | Other | 3hmp | A | | 7-chloro-n-(cyclopropylmethyl)quinazolin-4-amine | Human | 4728 | |
| TTK | TTK | Other | 5ap7 | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 6100 | |
| TTK | TTK | Other | 4c4e | A | B | - | Human | 4726 | |
| TTK | TTK | Other | 4o6l | B | | n-[(1r)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1h-indazole-5-carboxamide | Human | 4720 | |
| TTK | TTK | Other | 5eh0 | A | | n2-(2-methoxy-4-(1-methyl-1h-pyrazol-4-yl)phenyl)-n8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine | Human | 6850 | |
| TTK | TTK | Other | 4d2s | A | | n-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1h-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 4717 | |
| TTK | TTK | Other | 5ap5 | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6104 | |
| TTK | TTK | Other | 5eho | A | | ~{n}8-cyclohexyl-~{n}2-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine | Human | 7257 | |
