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Search results (32 entries covering 14 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
TNK2 (ACK)AckTK8fe9An-[(1s)-1-benzyl-2-[(6-chloro-2-oxo-1h-quinolin-4-yl)methylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1h-quinoline-6-carboHuman14676
TNK2 (ACK)AckTK6vqmB2-({4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6h-pyrimido[5,4-d][1,3]benzodiazepin-6-oneHuman13290
TNK2 (ACK)AckTK6vqmA2-({4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6h-pyrimido[5,4-d][1,3]benzodiazepin-6-oneHuman13289
TNK2 (ACK)AckTK5zxbAAn-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamideHuman10492
TNK2 (ACK)AckTK4id7Acis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanolHuman3401
TNK2 (ACK)AckTK4hzsA-Human3407
TNK2 (ACK)AckTK5zxbABn-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamideHuman10494
TNK2 (ACK)AckTK4hzrAB-Human3399
TNK2 (ACK)AckTK4hzrBA-Human3396
TNK2 (ACK)AckTK3eqrBn~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-n~6~-(4-piperazin-1-ylphenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,6-diamineHuman3406
TNK2 (ACK)AckTK1u4dBdebromohymenialdisineHuman3392
TNK2 (ACK)AckTK3eqpBn-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamideHuman3402
TNK2 (ACK)AckTK7kp6AB5-chloro-n~2~-[4-(4-methylpiperazin-1-yl)phenyl]-n~4~-{[(2r)-oxolan-2-yl]methyl}pyrimidine-2,4-diamineHuman14103
TNK2 (ACK)AckTK1u46A-Human3411
TNK2 (ACK)AckTK5zxbBAn-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamideHuman10493
TNK2 (ACK)AckTK1u54Aphosphomethylphosphonic acid adenylate esterHuman3409
TNK2 (ACK)AckTK4hzsB-Human3400
TNK2 (ACK)AckTK4ewhA6-{4-[2-(dimethylamino)ethoxy]phenyl}-n-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-amineHuman3410
TNK2 (ACK)AckTK3eqpAn-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamideHuman3403
TNK2 (ACK)AckTK4ewhB6-{4-[2-(dimethylamino)ethoxy]phenyl}-n-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-amineHuman3405
TNK2 (ACK)AckTK4hzsD-Human3404
TNK2 (ACK)AckTK4hzsC-Human3393
TNK2 (ACK)AckTK4hzrBB-Human3391
TNK2 (ACK)AckTK7kp6AA5-chloro-n~2~-[4-(4-methylpiperazin-1-yl)phenyl]-n~4~-{[(2r)-oxolan-2-yl]methyl}pyrimidine-2,4-diamineHuman14104
TNK2 (ACK)AckTK1u4dAdebromohymenialdisineHuman3398
TNK2 (ACK)AckTK8hmtAB6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2s)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-oneHuman15010
TNK2 (ACK)AckTK8hmtAA6-(2-bromophenyl)-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[[(2s)-oxolan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-oneHuman15009
TNK2 (ACK)AckTK5zxbBBn-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2h)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamideHuman10495
TNK2 (ACK)AckTK1u46B-Human3408
TNK2 (ACK)AckTK3eqrAn~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-n~6~-(4-piperazin-1-ylphenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,6-diamineHuman3395
TNK2 (ACK)AckTK4hzrAA-Human3394
TNK2 (ACK)AckTK1u54Bphosphomethylphosphonic acid adenylate esterHuman3397
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