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Search results (17 entries covering 14 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
PTK2B (PYK2)FAKTK8ygxAB-Human15244
PTK2B (PYK2)FAKTK8ygxAA-Human15245
PTK2B (PYK2)FAKTK3fzrAn-methyl-n-{2-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]phenyl}methanesulfonamideHuman87
PTK2B (PYK2)FAKTK3cc6AA-Human93
PTK2B (PYK2)FAKTK5tobAn-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamideHuman8686
PTK2B (PYK2)FAKTK3cc6AB-Human92
PTK2B (PYK2)FAKTK5to8A25-(methylsulfonyl)-8-(trifluoromethyl)-5,17,18,21,22,23,24,25-octahydro-12h-7,11-(azeno)-16,13-(metheno)pyrido[3,2-i]pyrrolo[1,2-q][1,3,7,11,17]pentaazacyclohenicosin-20(6h)-oneHuman7316
PTK2B (PYK2)FAKTK3fzoA-Human95
PTK2B (PYK2)FAKTK4h1jA1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(4-methoxy-2-methylphenyl)-1h-pyrazol-5-yl]ureaHuman91
PTK2B (PYK2)FAKTK3h3cA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman96
PTK2B (PYK2)FAKTK3fzpAphosphothiophosphoric acid-adenylate esterHuman88
PTK2B (PYK2)FAKTK3fzsA1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-ureaHuman94
PTK2B (PYK2)FAKTK3et7A5-{[4-{[2-(pyrrolidin-1-ylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,3-dihydro-2h-indol-2-oneHuman90
PTK2B (PYK2)FAKTK3fztA1-[5-tert-butyl-2-(4-methylphenyl)-1,2-dihydro-3h-pyrazol-3-ylidene]-3-{3-[(pyridin-3-yloxy)methyl]-1h-pyrazol-5-yl}ureaHuman86
PTK2B (PYK2)FAKTK4h1mA7-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)-n-(propan-2-yl)-1h-indole-2-carboxamideHuman89
PTK2B (PYK2)FAKTK8xoxAAn-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamideHuman15171
PTK2B (PYK2)FAKTK8xoxABn-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamideHuman15172
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