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Search results (24 entries covering 6 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
File
PTK6 (BRK)
Src
TK
5h2u
B
B
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7337
PTK6 (BRK)
Src
TK
5h2u
D
A
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7344
PTK6 (BRK)
Src
TK
6cz3
A
B
(3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone
Human
9999
PTK6 (BRK)
Src
TK
5d7v
D
B
-
Human
6952
PTK6 (BRK)
Src
TK
5d7v
D
A
-
Human
6948
PTK6 (BRK)
Src
TK
5h2u
D
B
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7340
PTK6 (BRK)
Src
TK
5d7v
A
A
-
Human
6953
PTK6 (BRK)
Src
TK
5h2u
C
B
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7342
PTK6 (BRK)
Src
TK
5da3
A
B
(2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone
Human
6988
PTK6 (BRK)
Src
TK
6cz2
A
B
-
Human
10031
PTK6 (BRK)
Src
TK
5d7v
C
A
-
Human
6949
PTK6 (BRK)
Src
TK
6cz4
A
B
2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide
Human
10000
PTK6 (BRK)
Src
TK
5d7v
B
B
-
Human
6951
PTK6 (BRK)
Src
TK
6cz3
A
A
(3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone
Human
10001
PTK6 (BRK)
Src
TK
5da3
A
A
(2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone
Human
6989
PTK6 (BRK)
Src
TK
6cz2
A
A
-
Human
10030
PTK6 (BRK)
Src
TK
6cz4
A
A
2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide
Human
9998
PTK6 (BRK)
Src
TK
5d7v
C
B
-
Human
6954
PTK6 (BRK)
Src
TK
5h2u
C
A
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7341
PTK6 (BRK)
Src
TK
5d7v
A
B
-
Human
6950
PTK6 (BRK)
Src
TK
5h2u
B
A
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7339
PTK6 (BRK)
Src
TK
5h2u
A
A
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7338
PTK6 (BRK)
Src
TK
5d7v
B
A
-
Human
6955
PTK6 (BRK)
Src
TK
5h2u
A
B
n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Human
7343
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