| SYK | Syk | TK | 6zcr | A | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | 13630 | |
| SYK | Syk | TK | 4px6 | A | A | 7-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)pyrido[4,3-d]pyrimidin-4(3h)-one | Human | 1200 | |
| SYK | Syk | TK | 6zcu | A | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | 13640 | |
| SYK | Syk | TK | 3srv | B | A | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1181 | |
| SYK | Syk | TK | 4yjo | A | B | 5-chloro-n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | 6119 | |
| SYK | Syk | TK | 4yjr | A | A | 3-(1h-indazol-4-yl{2-[(1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}amino)propan-1-ol | Human | 6113 | |
| SYK | Syk | TK | 4yjq | A | B | 3-[1h-indazol-4-yl(2-{[3-(4-methyl-1,3-oxazol-5-yl)phenyl]amino}pyrimidin-4-yl)amino]propan-1-ol | Human | 6123 | |
| SYK | Syk | TK | 4yjr | A | C | 3-(1h-indazol-4-yl{2-[(1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}amino)propan-1-ol | Human | 6122 | |
| SYK | Syk | TK | 4pv0 | A | | 4-[(3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzoyl)amino]benzoic acid | Human | 1161 | |
| SYK | Syk | TK | 3srv | B | B | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1206 | |
| SYK | Syk | TK | 5lma | A | B | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | 7049 | |
| SYK | Syk | TK | 1xbc | A | A | staurosporine | Human | 1165 | |
| SYK | Syk | TK | 4fyn | A | A | 3-[8-({4-[ethyl(2-hydroxyethyl)amino]phenyl}amino)imidazo[1,2-a]pyrazin-5-yl]phenol | Human | 1174 | |
| SYK | Syk | TK | 3emg | A | | 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-n-[(1s)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide | Human | 1183 | |
| SYK | Syk | TK | 6hm7 | A | B | 7-[2-methoxy-6-[(4-methylpyridin-2-yl)methoxy]phenyl]-2,3,4,5-tetrahydro-1~{h}-3-benzazepine | Human | 10615 | |
| SYK | Syk | TK | 4fl2 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1191 | |
| SYK | Syk | TK | 4rx8 | A | A | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide | Human | 1158 | |
| SYK | Syk | TK | 3tub | A | | 1-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-3-[(1r,2s)-2-phenylcyclopropyl]urea | Human | 1179 | |
| SYK | Syk | TK | 4xg7 | A | B | 1-[(3-methyl-1-{2-[(1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6318 | |
| SYK | Syk | TK | 5lma | A | C | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | 7044 | |
| SYK | Syk | TK | 1xbb | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1184 | |
| SYK | Syk | TK | 3srv | A | A | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1154 | |
| SYK | Syk | TK | 5lmb | A | B | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | 7046 | |
| SYK | Syk | TK | 3fqe | A | | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1155 | |
| SYK | Syk | TK | 5tiu | A | A | 5-{[(2s)-2-aminopropyl]amino}-3-(1h-indol-2-yl)pyrazine-2-carboxamide | Human | 7350 | |
| SYK | Syk | TK | 4rx8 | A | B | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide | Human | 1168 | |
| SYK | Syk | TK | 4yjp | A | | 2-[{2-[(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)amino]pyrimidin-4-yl}(1h-indazol-4-yl)amino]ethanol | Human | 6115 | |
| SYK | Syk | TK | 4f4p | A | B | n-{6-[3-(piperazin-1-yl)phenyl]pyridin-2-yl}-4-(trifluoromethyl)pyridin-2-amine | Human | 1156 | |
| SYK | Syk | TK | 4dfn | A | A | 3-amino-6-[3-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-[(1r,2r,3s,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamide | Human | 1201 | |
| SYK | Syk | TK | 5lmb | A | A | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | 7050 | |
| SYK | Syk | TK | 4dfl | A | | 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-n-(piperidin-4-ylmethyl)pyrazine-2-carboxamide | Human | 1152 | |
| SYK | Syk | TK | 6zcs | A | B | (3~{r},4~{r})-~{n}4-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]oxane-3,4-diamine | Human | 13641 | |
| SYK | Syk | TK | 4fyo | A | A | 4-{[(3s)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid | Human | 1180 | |
| SYK | Syk | TK | 4i0r | A | B | n-(propan-2-yl)-2-(3,4,5-trimethoxyphenyl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1175 | |
| SYK | Syk | TK | 3fqs | A | B | 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one | Human | 1202 | |
| SYK | Syk | TK | 8bi2 | A | | 10,13,23-trimethyl-16-oxa-2,4,8,9,13,19,23,30-octazapentacyclo[19.5.2.1^{3,7}.1^{8,11}.0^{24,28}]triaconta-1(27),3,5,7(30),9,11(29),21,24(28),25-nonaen-20-one | Human | 14779 | |
| SYK | Syk | TK | 4fl3 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1170 | |
| SYK | Syk | TK | 5tt7 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | 7283 | |
| SYK | Syk | TK | 4i0s | A | A | 2-(6-chloro-1-methyl-1h-indazol-3-yl)-n-(propan-2-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1157 | |
| SYK | Syk | TK | 4fyo | A | B | 4-{[(3s)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid | Human | 1205 | |
| SYK | Syk | TK | 3fqh | A | | n-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indole-5-carboxamide | Human | 1203 | |
| SYK | Syk | TK | 5cy3 | A | A | (5r)-5-[(1r)-1-{[6-(1-methyl-1h-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one | Human | 6058 | |
| SYK | Syk | TK | 3srv | A | B | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1162 | |
| SYK | Syk | TK | 4rx7 | A | A | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide | Human | 1189 | |
| SYK | Syk | TK | 5tr6 | A | A | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1h-pyrazol-4-yl)-1,2-dihydro-3h-pyrrolo[3,4-c]pyridin-3-one | Human | 7282 | |
| SYK | Syk | TK | 1xbb | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1196 | |
| SYK | Syk | TK | 4fz7 | A | B | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1177 | |
| SYK | Syk | TK | 4yjt | A | A | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | 6125 | |
| SYK | Syk | TK | 4fyn | A | B | 3-[8-({4-[ethyl(2-hydroxyethyl)amino]phenyl}amino)imidazo[1,2-a]pyrazin-5-yl]phenol | Human | 1197 | |
| SYK | Syk | TK | 5lmb | B | A | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | 7045 | |
| SYK | Syk | TK | 1xba | A | | - | Human | 1193 | |
| SYK | Syk | TK | 4i0s | A | B | 2-(6-chloro-1-methyl-1h-indazol-3-yl)-n-(propan-2-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1166 | |
| SYK | Syk | TK | 6vov | B | | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | 12040 | |
| SYK | Syk | TK | 6hm6 | A | A | 2-(4-methylphenyl)-3-(pyridin-2-ylmethoxy)pyridine | Human | 10614 | |
| SYK | Syk | TK | 3tuc | A | | 1-benzyl-n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 1195 | |
| SYK | Syk | TK | 4xg2 | A | | - | Human | 6309 | |
| SYK | Syk | TK | 1xbc | A | B | staurosporine | Human | 1207 | |
| SYK | Syk | TK | 3fqh | B | | n-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indole-5-carboxamide | Human | 1171 | |
| SYK | Syk | TK | 5c26 | A | | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide | Human | 6131 | |
| SYK | Syk | TK | 4px6 | A | B | 7-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)pyrido[4,3-d]pyrimidin-4(3h)-one | Human | 1204 | |
| SYK | Syk | TK | 4i0t | A | B | n-tert-butyl-2-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1164 | |
| SYK | Syk | TK | 4yjq | A | A | 3-[1h-indazol-4-yl(2-{[3-(4-methyl-1,3-oxazol-5-yl)phenyl]amino}pyrimidin-4-yl)amino]propan-1-ol | Human | 6114 | |
| SYK | Syk | TK | 5cy3 | A | B | (5r)-5-[(1r)-1-{[6-(1-methyl-1h-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one | Human | 6056 | |
| SYK | Syk | TK | 3tud | A | | n-{4-methyl-3-[8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]phenyl}-3-(trifluoromethyl)benzamide | Human | 1176 | |
| SYK | Syk | TK | 4rx7 | A | B | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide | Human | 1182 | |
| SYK | Syk | TK | 5cxh | A | | (4r)-4-[(1r)-1-{[6-(3,4-dimethoxyphenyl)[1,3]thiazolo[5,4-c]pyridin-4-yl]oxy}ethyl]pyrrolidin-2-one | Human | 6057 | |
| SYK | Syk | TK | 4dfn | A | B | 3-amino-6-[3-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-[(1r,2r,3s,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamide | Human | 1199 | |
| SYK | Syk | TK | 4yjo | A | A | 5-chloro-n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | 6120 | |
| SYK | Syk | TK | 6zcs | A | A | (3~{r},4~{r})-~{n}4-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]oxane-3,4-diamine | Human | 13639 | |
| SYK | Syk | TK | 4i0t | A | A | n-tert-butyl-2-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1198 | |
| SYK | Syk | TK | 4yjv | A | B | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | 6148 | |
| SYK | Syk | TK | 4i0r | A | A | n-(propan-2-yl)-2-(3,4,5-trimethoxyphenyl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 1192 | |
| SYK | Syk | TK | 5cxz | A | A | n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine | Human | 6040 | |
| SYK | Syk | TK | 4fl1 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1160 | |
| SYK | Syk | TK | 4xg9 | B | | 1-[(1-{2-[(3-chloro-1,2-dimethyl-1h-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6315 | |
| SYK | Syk | TK | 5lma | A | A | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | 7047 | |
| SYK | Syk | TK | 4xg6 | A | | 1-[(1-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-3-methyl-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6312 | |
| SYK | Syk | TK | 4xg8 | A | | 1-[(1-{2-[(3-chloro-1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6317 | |
| SYK | Syk | TK | 6zcx | A | A | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-piperidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | 13642 | |
| SYK | Syk | TK | 3fqs | A | A | 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one | Human | 1169 | |
| SYK | Syk | TK | 4yjs | A | | 3-[{2-[(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)amino]pyrimidin-4-yl}(1h-indazol-4-yl)amino]propan-1-ol | Human | 6117 | |
| SYK | Syk | TK | 4xg8 | C | | 1-[(1-{2-[(3-chloro-1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6310 | |
| SYK | Syk | TK | 4xg9 | A | | 1-[(1-{2-[(3-chloro-1,2-dimethyl-1h-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6311 | |
| SYK | Syk | TK | 4xg3 | A | | 4-{[5-fluoro-4-(3-{[(3r)-3-hydroxypyrrolidin-1-yl]methyl}-4-methyl-1h-pyrrol-1-yl)pyrimidin-2-yl]amino}-2,6-dimethylphenyl methanesulfonate | Human | 6308 | |
| SYK | Syk | TK | 4xg4 | A | | (3r)-1-{[1-(5-fluoro-2-{[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]amino}pyrimidin-4-yl)-4-methyl-1h-pyrrol-3-yl]methyl}pyrrolidin-3-ol | Human | 6319 | |
| SYK | Syk | TK | 5ghv | B | | 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1h-pyrrol-3-yl}methyl)azetidin-3-ol | Human | 6742 | |
| SYK | Syk | TK | 5ghv | A | | 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1h-pyrrol-3-yl}methyl)azetidin-3-ol | Human | 6743 | |
| SYK | Syk | TK | 4xg3 | B | | 4-{[5-fluoro-4-(3-{[(3r)-3-hydroxypyrrolidin-1-yl]methyl}-4-methyl-1h-pyrrol-1-yl)pyrimidin-2-yl]amino}-2,6-dimethylphenyl methanesulfonate | Human | 6314 | |
| SYK | Syk | TK | 4rss | A | B | 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1h-indol-5-yl)amino]pyrimidin-4-yl}-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6170 | |
| SYK | Syk | TK | 4yjt | A | B | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | 6118 | |
| SYK | Syk | TK | 4xg7 | A | A | 1-[(3-methyl-1-{2-[(1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6316 | |
| SYK | Syk | TK | 4rss | A | A | 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1h-indol-5-yl)amino]pyrimidin-4-yl}-1h-pyrazol-4-yl)methyl]azetidin-3-ol | Human | 6169 | |
| SYK | Syk | TK | 4f4p | A | A | n-{6-[3-(piperazin-1-yl)phenyl]pyridin-2-yl}-4-(trifluoromethyl)pyridin-2-amine | Human | 1178 | |
| SYK | Syk | TK | 4yjt | A | C | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | 6124 | |
| SYK | Syk | TK | 4puz | A | | 6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine | Human | 1163 | |
| SYK | Syk | TK | 4fl3 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1172 | |
| SYK | Syk | TK | 5lmb | B | B | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | 7048 | |
| SYK | Syk | TK | 4puz | B | | 6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine | Human | 1153 | |
| SYK | Syk | TK | 5t68 | B | | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | 7120 | |
| SYK | Syk | TK | 5t68 | A | | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | 7119 | |
| SYK | Syk | TK | 5tr6 | A | B | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1h-pyrazol-4-yl)-1,2-dihydro-3h-pyrrolo[3,4-c]pyridin-3-one | Human | 7284 | |
| SYK | Syk | TK | 6vov | A | | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | 12041 | |
| SYK | Syk | TK | 4fz6 | A | A | n-{6-[(2s)-2-methylpyrrolidin-1-yl]pyridin-2-yl}-6-phenylimidazo[1,2-b]pyridazin-8-amine | Human | 1173 | |
| SYK | Syk | TK | 4rx9 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1194 | |
| SYK | Syk | TK | 5y5u | B | | 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8h-pyrido[4,3-d]pyrimidin-5-one | Human | 10029 | |
| SYK | Syk | TK | 5tt7 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | 7281 | |
| SYK | Syk | TK | 5tiu | A | B | 5-{[(2s)-2-aminopropyl]amino}-3-(1h-indol-2-yl)pyrazine-2-carboxamide | Human | 7349 | |
| SYK | Syk | TK | 3vf8 | A | | 3-[5-(5-ethoxy-6-fluoro-1h-benzimidazol-2-yl)-1h-pyrazol-4-yl]-1,1-diethylurea | Human | 1187 | |
| SYK | Syk | TK | 4fz6 | A | B | n-{6-[(2s)-2-methylpyrrolidin-1-yl]pyridin-2-yl}-6-phenylimidazo[1,2-b]pyridazin-8-amine | Human | 1185 | |
| SYK | Syk | TK | 4gfg | A | | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1188 | |
| SYK | Syk | TK | 3vf9 | A | | 3-{2-[5-(difluoromethyl)-2h-thieno[3,2-c]pyrazol-3-yl]-1h-indol-6-yl}pentan-3-ol | Human | 1159 | |
| SYK | Syk | TK | 6hm7 | A | A | 7-[2-methoxy-6-[(4-methylpyridin-2-yl)methoxy]phenyl]-2,3,4,5-tetrahydro-1~{h}-3-benzazepine | Human | 10612 | |
| SYK | Syk | TK | 5c27 | A | | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-n-[4-(methylcarbamoyl)phenyl]benzamide | Human | 6132 | |
| SYK | Syk | TK | 4fl1 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1167 | |
| SYK | Syk | TK | 4wnm | A | | n~3~-(tetrahydro-2h-pyran-4-yl)-n~6~-[5-(tetrahydro-2h-pyran-4-ylmethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-1h-indazole-3,6-diamine | Human | 6358 | |
| SYK | Syk | TK | 5cxz | A | B | n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine | Human | 6041 | |
| SYK | Syk | TK | 4yjv | A | C | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | 6149 | |
| SYK | Syk | TK | 6zcp | A | | 7-[[4-[4-[(dimethylamino)methyl]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{n},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide | Human | 13632 | |
| SYK | Syk | TK | 6zcy | A | A | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | 13634 | |
| SYK | Syk | TK | 6zcq | A | | 7-[[4-[4-[[(3~{r},4~{r})-3-azanyloxan-4-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{n},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide | Human | 13633 | |
| SYK | Syk | TK | 6zcu | A | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | 13635 | |
| SYK | Syk | TK | 6zcx | A | B | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-piperidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | 13637 | |
| SYK | Syk | TK | 6zcy | A | B | ~{n},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{r})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide | Human | 13638 | |
| SYK | Syk | TK | 6zc0 | A | | ~{n},~{n}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine | Human | 13636 | |
| SYK | Syk | TK | 4yju | A | B | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-5-fluoro-n~4~-(1h-indazol-4-yl)-n~4~-methylpyrimidine-2,4-diamine | Human | 6121 | |
| SYK | Syk | TK | 5y5t | A | | 2-[[(1s,2s)-2-azanylcyclohexyl]amino]-4-[(4-methylsulfonylphenyl)amino]-6h-pyrido[4,3-d]pyrimidin-5-one | Human | 10028 | |
| SYK | Syk | TK | 6hm6 | A | B | 2-(4-methylphenyl)-3-(pyridin-2-ylmethoxy)pyridine | Human | 10613 | |
| SYK | Syk | TK | 4yjr | A | B | 3-(1h-indazol-4-yl{2-[(1-methyl-1h-indazol-5-yl)amino]pyrimidin-4-yl}amino)propan-1-ol | Human | 6116 | |
| SYK | Syk | TK | 4yjv | A | A | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | 6150 | |
| SYK | Syk | TK | 4fz7 | A | A | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1186 | |
| SYK | Syk | TK | 6zcr | A | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | 13631 | |
| SYK | Syk | TK | 5y5u | A | | 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8h-pyrido[4,3-d]pyrimidin-5-one | Human | 10027 | |
| SYK | Syk | TK | 4rx9 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1190 | |
| SYK | Syk | TK | 6ssb | A | | ~{n}-[4-[5-[(dimethylamino)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-yl]-3-methyl-1-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,5-a]pyridin-7-amine | Human | 12817 | |
| SYK | Syk | TK | 4yju | A | A | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-5-fluoro-n~4~-(1h-indazol-4-yl)-n~4~-methylpyrimidine-2,4-diamine | Human | 6112 | |
| SYK | Syk | TK | 8x5k | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15103 | |
| SYK | Syk | TK | 8x5k | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15102 | |
