KLIFS - the structural kinase database

Search results (13 entries covering 8 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details
TEK (TIE2)	Tie	TK	2oo8	X		n-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)phenyl}-4-methyl-3-[(3-pyrimidin-4-ylpyridin-2-yl)amino]benzamide	Human	5556
TEK (TIE2)	Tie	TK	4x3j	A		1-[4-(4-amino-5-oxopyrido[2,3-d]pyrimidin-8(5h)-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea	Human	5552
TEK (TIE2)	Tie	TK	3l8p	A		2-methyl-11-(1-methylethyl)-8-[(2s)-tetrahydro-2h-pyran-2-yl]-2,11,12,13-tetrahydro-4h-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one	Human	5548
TEK (TIE2)	Tie	TK	1fvr	B		-	Human	5554
TEK (TIE2)	Tie	TK	2wqb	A		2-[3-(cyclohexylmethyl)-5-phenyl-imidazol-4-yl]-[1,3]thiazolo[4,5-e]pyrimidin-7-amine	Human	5553
TEK (TIE2)	Tie	TK	2p4i	A		4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamide	Human	5549
TEK (TIE2)	Tie	TK	6mwe	B	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	10713
TEK (TIE2)	Tie	TK	6mwe	B	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	10712
TEK (TIE2)	Tie	TK	1fvr	A		-	Human	5551
TEK (TIE2)	Tie	TK	2osc	A		n-{4-methyl-3-[(3-pyrimidin-4-ylpyridin-2-yl)amino]phenyl}-3-(trifluoromethyl)benzamide	Human	5555
TEK (TIE2)	Tie	TK	2p4i	B		4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamide	Human	5550
TEK (TIE2)	Tie	TK	6mwe	A	A	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	10710
TEK (TIE2)	Tie	TK	6mwe	A	B	4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide	Human	10711