| RIPK1 | RIPK | TKL | 8i2n | A | | ~{n}-methyl-1-[4-[[[1-methyl-5-(phenylmethyl)pyrazol-3-yl]carbonylamino]methyl]phenyl]benzimidazole-5-carboxamide | Human | 15186 | |
| RIPK1 | RIPK | TKL | 6ocq | B | B | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11045 | |
| RIPK1 | RIPK | TKL | 4ith | B | B | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 571 | |
| RIPK1 | RIPK | TKL | 6nw2 | A | B | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11041 | |
| RIPK1 | RIPK | TKL | 6ocq | A | A | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11046 | |
| RIPK1 | RIPK | TKL | 6c3e | A | A | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9750 | |
| RIPK1 | RIPK | TKL | 4ith | B | A | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 564 | |
| RIPK1 | RIPK | TKL | 4neu | B | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 568 | |
| RIPK1 | RIPK | TKL | 4itj | B | B | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 574 | |
| RIPK1 | RIPK | TKL | 5hx6 | A | | 5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide | Human | 6417 | |
| RIPK1 | RIPK | TKL | 7fd0 | A | | n-[(3s)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide | Human | 14070 | |
| RIPK1 | RIPK | TKL | 6r5f | A | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11038 | |
| RIPK1 | RIPK | TKL | 5tx5 | B | B | gsk2982772 | Human | 8215 | |
| RIPK1 | RIPK | TKL | 6c4d | B | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9752 | |
| RIPK1 | RIPK | TKL | 4itj | B | A | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 565 | |
| RIPK1 | RIPK | TKL | 5tx5 | A | A | gsk2982772 | Human | 8214 | |
| RIPK1 | RIPK | TKL | 4itj | A | A | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 575 | |
| RIPK1 | RIPK | TKL | 4itj | A | B | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 572 | |
| RIPK1 | RIPK | TKL | 6nw2 | B | A | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11039 | |
| RIPK1 | RIPK | TKL | 6nw2 | B | B | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11043 | |
| RIPK1 | RIPK | TKL | 6c4d | D | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9753 | |
| RIPK1 | RIPK | TKL | 6nyh | A | | (5s)-n-[(3s)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1h-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5h-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide | Human | 11057 | |
| RIPK1 | RIPK | TKL | 7fcz | A | | n-[(3s)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide | Human | 14071 | |
| RIPK1 | RIPK | TKL | 7ydx | A | B | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-phenylethyl]indole-3-carboxamide | Human | 14710 | |
| RIPK1 | RIPK | TKL | 7ydx | A | A | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-phenylethyl]indole-3-carboxamide | Human | 14711 | |
| RIPK1 | RIPK | TKL | 7xmk | A | | 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide | Human | 14716 | |
| RIPK1 | RIPK | TKL | 4iti | B | B | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 569 | |
| RIPK1 | RIPK | TKL | 6r5f | C | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11042 | |
| RIPK1 | RIPK | TKL | 6c4d | A | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9754 | |
| RIPK1 | RIPK | TKL | 4ith | A | A | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 566 | |
| RIPK1 | RIPK | TKL | 4ith | A | B | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 567 | |
| RIPK1 | RIPK | TKL | 6r5f | B | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11044 | |
| RIPK1 | RIPK | TKL | 5tx5 | A | B | gsk2982772 | Human | 8217 | |
| RIPK1 | RIPK | TKL | 6rln | B | | ~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide | Human | 11382 | |
| RIPK1 | RIPK | TKL | 6c4d | C | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9756 | |
| RIPK1 | RIPK | TKL | 6ocq | A | B | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11047 | |
| RIPK1 | RIPK | TKL | 6hho | A | | 6-[4-[(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | Human | 10783 | |
| RIPK1 | RIPK | TKL | 6rln | A | | ~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide | Human | 11383 | |
| RIPK1 | RIPK | TKL | 4iti | A | A | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 570 | |
| RIPK1 | RIPK | TKL | 4iti | A | B | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 563 | |
| RIPK1 | RIPK | TKL | 4neu | B | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 573 | |
| RIPK1 | RIPK | TKL | 6c3e | B | B | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9757 | |
| RIPK1 | RIPK | TKL | 4neu | A | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 561 | |
| RIPK1 | RIPK | TKL | 6hho | B | | 6-[4-[(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | Human | 10784 | |
| RIPK1 | RIPK | TKL | 6ocq | B | A | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11048 | |
| RIPK1 | RIPK | TKL | 6nyh | B | | (5s)-n-[(3s)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1h-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5h-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide | Human | 11056 | |
| RIPK1 | RIPK | TKL | 4neu | A | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 576 | |
| RIPK1 | RIPK | TKL | 4iti | B | A | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 562 | |
| RIPK1 | RIPK | TKL | 6c3e | B | A | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9755 | |
| RIPK1 | RIPK | TKL | 5tx5 | B | A | gsk2982772 | Human | 8216 | |
| RIPK1 | RIPK | TKL | 6r5f | D | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11037 | |
| RIPK1 | RIPK | TKL | 5hx6 | B | | 5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide | Human | 6418 | |
| RIPK1 | RIPK | TKL | 6c3e | A | B | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9751 | |
| RIPK1 | RIPK | TKL | 6nw2 | A | A | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11040 | |
