| DYRK1A | DYRK | CMGC | 6ej4 | A | | 3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)aniline | Human | 10520 | 0.51 | |
| DYRK1A | DYRK | CMGC | 6eif | A | | 4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamide | Human | 10534 | 0.54 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9786 | 0.60 | |
| Abl1 (ABL1) | Abl | TK | 2qoh | A | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5707 | 0.47 | |
| Abl1 (ABL1) | Abl | TK | 2z60 | A | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5735 | 0.47 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 1zys | A | | n-{5-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}nicotinamide | Human | 1655 | 0.45 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9783 | 0.60 | |
| Abl1 (ABL1) | Abl | TK | 2qoh | B | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5716 | 0.47 | |
| LIMK1 | LISK | TKL | 7ats | A | | n-[3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]benzenesulfonamide | Human | 13164 | 0.42 | |
| JAK3 | JakA | TK | 7apf | B | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13132 | 0.49 | |
| MAP3K8 (COT) | STE-Unique | STE | 4y85 | C | | 5-[5-(1h-indol-3-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]-1,3,4-oxadiazol-2-amine | Human | 424 | 0.43 | |
| MAP3K8 (COT) | STE-Unique | STE | 4y85 | A | | 5-[5-(1h-indol-3-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]-1,3,4-oxadiazol-2-amine | Human | 427 | 0.43 | |
| JAK3 | JakA | TK | 7apg | B | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13131 | 0.42 | |
| JAK3 | JakA | TK | 7apg | C | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13140 | 0.42 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bku | A | | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 8687 | 0.62 | |
| DYRK1A | DYRK | CMGC | 6eif | B | | 4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamide | Human | 10544 | 0.54 | |
| ABL1 | Abl | TK | 7cc2 | A | | [4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methyl-phenyl]boronic acid | Human | 13620 | 0.52 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 4qyf | A | | 4-[3-amino-6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid | Human | 1622 | 0.41 | |
| JAK3 | JakA | TK | 7apg | D | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13138 | 0.42 | |
| JAK3 | JakA | TK | 7apg | C | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13139 | 0.42 | |
| MAP3K8 (COT) | STE-Unique | STE | 4y85 | B | | 5-[5-(1h-indol-3-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]-1,3,4-oxadiazol-2-amine | Human | 429 | 0.43 | |
| JAK3 | JakA | TK | 7apg | D | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13133 | 0.42 | |
| JAK3 | JakA | TK | 7apg | A | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13134 | 0.42 | |
| JAK3 | JakA | TK | 7apg | A | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13135 | 0.42 | |
| DYRK1A | DYRK | CMGC | 6eif | C | | 4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamide | Human | 10525 | 0.54 | |
| DYRK1A | DYRK | CMGC | 6ej4 | D | | 3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)aniline | Human | 10545 | 0.51 | |
| AAK1 | NAK | Other | 5l4q | A | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6679 | 0.44 | |
| AAK1 | NAK | Other | 5l4q | B | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6678 | 0.44 | |
| AAK1 | NAK | Other | 5l4q | B | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6680 | 0.44 | |
| AAK1 | NAK | Other | 5l4q | A | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6677 | 0.44 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 4qye | A | | 4-[6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid | Human | 1601 | 0.44 | |
| JAK3 | JakA | TK | 7apf | A | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13141 | 0.49 | |
| JAK3 | JakA | TK | 7apg | B | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13136 | 0.42 | |
| JAK3 | JakA | TK | 7apf | B | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13137 | 0.49 | |
| DYRK1A | DYRK | CMGC | 6ej4 | B | | 3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)aniline | Human | 10523 | 0.51 | |
| DYRK1A | DYRK | CMGC | 6ej4 | C | | 3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)aniline | Human | 10519 | 0.51 | |
| DYRK1A | DYRK | CMGC | 6eif | D | | 4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamide | Human | 10532 | 0.54 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9784 | 0.60 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9714 | 0.62 | |
| JAK3 | JakA | TK | 7apf | A | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13130 | 0.49 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9785 | 0.60 | |
| NEK2 | NEK | Other | 2wqo | A | | 4-[2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]benzoic acid | Human | 331 | 0.47 | |
| SGK1 | SGK | AGC | 3hdm | A | | 4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 3271 | 1.00 | |
| SGK1 | SGK | AGC | 3hdn | A | | [4-(5-naphthalen-2-yl-1h-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid | Human | 3270 | 0.60 | |
| INSR | InsR | TK | 3eta | B | B | 1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea | Human | 600 | 0.48 | |
| INSR | InsR | TK | 3eta | A | A | 1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea | Human | 590 | 0.48 | |
| INSR | InsR | TK | 3eta | A | B | 1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea | Human | 579 | 0.48 | |
| INSR | InsR | TK | 3eta | B | A | 1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea | Human | 588 | 0.48 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9716 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9715 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9713 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9711 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9709 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9710 | 0.62 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9708 | 0.62 | |
| ABL1 | Abl | TK | 7w7x | A | | 5-[5-(dimethylcarbamoyl)pyridin-3-yl]-3-(5-fluorosulfonyloxy-2-methoxy-phenyl)-1h-pyrrolo[2,3-b]pyridine | Human | 14196 | 0.41 | |
| MET | Met | TK | 7b3z | A | B | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13186 | 0.42 | |
| MET | Met | TK | 7b3z | A | A | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13181 | 0.42 | |
